Effects of image noise in muscle diffusion tensor (DT)-MRI assessed using numerical simulations.
Effects of image noise in muscle diffusion tensor (DT)-MRI assessed using numerical simulations.
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DOI:
10.1002/mrm.21707
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发表时间:
2008-10
影响因子:
3.3
通讯作者:
Damon, Bruce M.
中科院分区:
文献类型:
--
作者:
Damon, Bruce M.
Diffusion-tensor MRI (DT-MRI) studies of skeletal muscle provide information about muscle architecture, microstructure, and damage. However, the effects of noise, the diffusion weighting (b-) value, and partial volume artifacts on the estimation of the diffusion tensor (D) are unknown. This study investigated these issues using Monte Carlo simulations of 3×9 voxel regions of interest containing muscle, adipose tissue, and intermediate degrees of muscle volume fractions (fM). 1000 simulations were performed for each of 8 b-values and 11 SNR levels. The dependences of the eigenvalues (λ1-3), mean diffusivity ( ), fractional anisotropy (FA), and the angular deviation of the first eigenvector from its true value (α) were observed. For moderate b-values (b=435-725 s/mm2) and fM=1, an accuracy of 5% was obtained for λ1-3, , and FA with an SNR of 25. An accuracy of 1% was obtained for λ1-3, , and FA with fM=1 and SNR=50. For regions with fM=8/9, 5% accuracy was obtained with SNR=40. For α, SNR≥25 and ≥45 were required for ±4.5° uncertainty with fM=1 and fM=0.5, respectively; SNR≥60 was required for ±9° uncertainty in single muscle voxels. These findings may influence the design and interpretation of DT-MRI studies of muscle microstructure, damage, and architecture.
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影响因子:
3
作者:
Galbán, CJ;Maderwald, S;Ladd, ME
通讯作者:
Ladd, ME
影响因子:
2.2
作者:
Koay, Cheng Guan;Chang, Lin-Ching;Basser, Peter J.
通讯作者:
Basser, Peter J.
DOI:
10.1016/0304-4165(72)90084-0
发表时间:
1972-01-01
期刊:
BIOCHIMICA ET BIOPHYSICA ACTA
影响因子:
--
作者:
BELTON, PS;JACKSON, RR;PACKER, KJ
通讯作者:
PACKER, KJ
影响因子:
3.3
作者:
Damon, BM;Ding, ZH;Gore, JC
通讯作者:
Gore, JC
影响因子:
3.4
作者:
HAZLEWOOD, CF;CHANG, DC;WOESSNER, DE
通讯作者:
WOESSNER, DE