Anterior insular cortex and emotional awareness.

Anterior insular cortex and emotional awareness.
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DOI:
10.1002/cne.23368
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发表时间:
2013-10-15
影响因子:
2.5
通讯作者:
Fan, Jin
Fan, Jin
中科院分区:
医学3区
文献类型:
--
作者:
Gu, Xiaosi;Hof, Patrick R.;Friston, Karl J.;Fan, Jin

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本文综述了人类前岛叶皮层(AIC)在情绪意识中作用的基础,被定义为情绪的有意识体验。我们首先介绍了AIC的神经解剖学特征和关于情绪意识的现有研究成果。本研究以共情(他人情绪状态的认知和理解)为例,通过荟萃分析证明了AIC与前扣带皮层(ACC)共同激活,AIC与前扣带皮层在功能上可分离,AIC整合了刺激驱动和自上而下的信息,AIC是情绪意识的必要条件。我们提出了一个模型,其中AIC具有两个主要功能:将自下而上的内感受信号与自上而下的预测相结合,以产生当前的意识状态,并向内脏系统提供下行预测,为自主神经反射提供参考点。我们认为AIC对于情绪意识是至关重要和必要的。
This paper reviews the foundation for a role of the human anterior insular cortex (AIC) in emotional awareness, defined as the conscious experience of emotions. We first introduce the neuroanatomical features of AIC and existing findings on emotional awareness. Using empathy, the awareness and understanding of other people’s emotional states, as a test case, we then present evidence to demonstrate: 1) AIC and anterior cingulate cortex (ACC) are commonly coactivated as revealed by a meta-analysis, 2) AIC is functionally dissociable from ACC, 3) AIC integrates stimulus-driven and top-down information, and 4) AIC is necessary for emotional awareness. We propose a model in which AIC serves two major functions: integrating bottom-up interoceptive signals with top-down predictions to generate a current awareness state and providing descending predictions to visceral systems that provide a point of reference for autonomic reflexes. We argue that AIC is critical and necessary for emotional awareness.
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