Measurement of reaction time in the home for people with dementia: a feasibility study.
Measurement of reaction time in the home for people with dementia: a feasibility study.
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DOI：
10.1177/1099800411420862
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发表时间：
2013-04
影响因子：
2.5
通讯作者：
Howieson D
中科院分区：
文献类型：
--
作者：
Cole CS;Mennemeier M;Bost JE;Smith-Olinde L;Howieson D
认知能力下降是痴呆症的主要症状。准确测量认知变化，虽然对于测试干预措施以减缓认知下降至关重要，但在痴呆症患者（PWD）中可能具有挑战性。例如，实验室环境可能会导致焦虑并对表现产生负面影响。在健康人群中，研究人员通过在实验室环境中评估反应时间来测量认知的一个方面，即注意力。本重复测量研究调查了在参与者家中使用计算机化的PWD心理警觉任务（PVT）进行反应时测量的可行性。研究问题是（1）实验室控制可以在家庭中复制吗？(2)PWD在何处进行PVT试验最佳？（3）残疾人及其照顾者的偏好是什么？测试位置顺序不同的两组在2天内完成了12次反应时间评估。在后续的电话采访中，对照顾者和痴呆症患者的二元偏好进行了检查。完整的数据收集了14个二分体。虽然不同的设置在照明方面略有差异，但一天中的时间，温度和声音没有差异。两个地点之间的PVT性能没有显著差异，但第1天在家中测试的组比第1天在实验室测试的组表现更好。所有参与者都喜欢在家检查。在家里测量反应时间是可行的。家庭测试有助于最佳性能，参与者更喜欢家庭。
Cognitive decline is the cardinal symptom of dementia. Accurate measurement of changes in cognition, while essential for testing interventions to slow cognitive decline, can be challenging in people with dementia (PWD). For example, the laboratory environment may cause anxiety and negatively affect performance. In healthy people, researchers measure one aspect of cognition, attention, via assessing reaction times in a laboratory environment. This repeated measures study investigated the feasibility of reaction time measurement in participants’ homes using the computerized psychomotor vigilance task (PVT) for PWD. Research questions were (1) Can laboratory controls be replicated in the home? (2) Where do PWD perform PVT trials optimally? and, (3) What are the preferences of PWD and their caregivers? Two groups that differed by sequence of testing location completed 12 reaction time assessments over 2 days. Caregiver and person with dementia dyad preferences were examined in a follow-up phone interview. Complete data were collected from 14 dyads. Although there were slight differences in lighting between settings, time of day, temperature and sound did not differ. There were no significant differences in PVT performance between the two locations, but the group who tested in the home on Day 1 performed better than the group who tested in the lab on Day 1. All participants preferred home examination. It is feasible to measure reaction times in the home. Home testing contributes to optimal performance and participants preferred the home.
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DOI：
10.1073/pnas.0503082102
发表时间：
2005-12-06
影响因子：
11.1
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