T lymphocyte response to Neisseria gonorrhoeae porin in individuals with mucosal gonococcal infections.
T lymphocyte response to Neisseria gonorrhoeae porin in individuals with mucosal gonococcal infections.
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粘膜淋球菌感染个体中 T 淋巴细胞对淋病奈瑟菌孔蛋白的反应。
DOI：
10.1086/314969
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发表时间：
1999
期刊：
影响因子：
--
通讯作者：
Wetzler,LM
中科院分区：
文献类型：
--
作者：
Simpson,SD;Ho,Y;Rice,PA;Wetzler,LM
T lymphocytes from a majority of patients with urogenital gonococcal disease (67%–80%) proliferated on incubation with gonococcal porin (Por), compared with minimal induced proliferation of T lymphocytes from normal volunteers. A significant increase in Por-specific interleukin (IL)—4—producing CD4+T helper lymphocytes was seen in patients with mucosal gonococcal disease and not in normal controls. Similar results were observed in CD8+T lymphocytes from these patients. There was no measured increase in IL-2, IL-10, IL-12, interferon-γ, or tumor necrosis factor-α production by T lymphocytes from infected subjects on incubation with Por. Concomitant increases in IL-4 production in T lymphocytes from infected subjects expressing the mucosal addresin VLAα4/β7on their surface were also observed on Por incubation, but the increases were similar in T lymphocytes that were VLAα4/β7negative. In conclusion, mucosal gonococcal disease can induce Por-specific circulating T lymphocytes with a Th2 phenotype, and a portion of these Por-specific T lymphocytes can potentially traffic to mucosal surfaces.
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人粘膜地址素细胞粘附分子-1优先在肠道和相关淋巴组织中表达。
DOI：
--
发表时间：
1997
期刊：
The American journal of pathology
影响因子：
--
作者：
Briskin,M;Winsor-Hines,D;Shyjan,A;Cochran,N;Bloom,S;Wilson,J;McEvoy,LM;Butcher,EC;Kassam,N;Mackay,CR;Newman,W;Ringler,DJ
通讯作者：
Ringler,DJ
人类循环淋巴细胞的归巢潜力取决于激活部位：口服伤寒疫苗（而非肠胃外注射）会诱导循环抗体分泌细胞，这些细胞都带有将其引导至肠道的归巢受体。
DOI：
--
发表时间：
1997
期刊：
Journal of immunology (Baltimore, Md. : 1950)
影响因子：
--
作者：
Kantele,A;Kantele,JM;Savilahti,E;Westerholm,M;Arvilommi,H;Lazarovits,A;Butcher,EC;Mäkelä,PH
通讯作者：
Mäkelä,PH
细菌外膜作为模型系统
影响因子：
3.5
作者：
H. Perkins
通讯作者：
H. Perkins
脑膜炎奈瑟菌选择性损害 B 细胞功能。
影响因子：
4.3
作者：
J. Melancon;K. Gronvik;R. A. Murgita
通讯作者：
R. A. Murgita
人子宫内膜中独特的富含 CD8+ T 细胞的淋巴聚集体
影响因子：
5.5
作者：
G. Yeaman;P. Guyre;M. Fanger;J. Collins;H. White;W. Rathbun;K. Orndorff;Jorge L. Gonzalez;J. Stern;C. Wira
通讯作者：
C. Wira