Altered regional loading patterns on articular cartilage following meniscectomy are not fully restored by autograft meniscal transplantation.
Altered regional loading patterns on articular cartilage following meniscectomy are not fully restored by autograft meniscal transplantation.
复制标题
半月板切除术后关节软骨区域负荷模式的改变并不能通过自体半月板移植完全恢复。
DOI：
10.1016/j.joca.2014.12.003
复制
发表时间：
2015
影响因子：
7
通讯作者：
Maher,SA
中科院分区：
文献类型：
--
作者：
Wang,H;Chen,T;Gee,AO;Hutchinson,ID;Stoner,K;Warren,RF;Rodeo,SA;Maher,SA
目的量化胫骨关节软骨上的区域动态载荷模式的变化，在模拟行走后内侧髁切除术和关节移植，MethodsSeven新鲜冷冻人尸体膝关节进行了测试下的多向负荷模仿活动的步行，而接触应力的胫骨平台上同步记录使用电子传感器。每个膝关节在三种情况下进行测试：完整半月板、内侧半月板切除术和半月板移植。在不同的位置进行了评估和共同的负载模式，确定在不同的网站上的胫骨平台，使用一个既定的数值algorithm.ResultsThree区域模式被发现在胫骨平台上的完整的膝盖。内侧髁突切除后，位于内侧平台后部的第一模式的面积显著减小，而峰值载荷的幅度显著增加了120%。第二种模式位于外侧平台的中后部，向前和向外移位，但幅度不变。在内侧平台的软骨-软骨接触区的第三种模式是不存在的后椎间盘切除术。半月板移植在很大程度上恢复了第一种模式，但它没有恢复其他两个patterns.ConclusionThere是在区域负载模式的内侧和外侧胫骨平台以下内侧半月板切除术的网站依赖性的变化。即使在几何形状和材料特性保持不变的情况下使用自体骨移植物，载荷模式恢复的唯一区域是内侧平台的后部。
ObjectiveTo quantify the changes in regional dynamic loading patterns on tibial articular cartilage during simulated walking following medial meniscectomy and meniscal transplantation.MethodsSeven fresh frozen human cadaveric knees were tested under multidirectional loads mimicking the activity of walking, while the contact stresses on the tibial plateau were synchronously recorded using an electronic sensor. Each knee was tested for three conditions: intact meniscus, medial meniscectomy, and meniscal transplantation. The loading profiles at different locations were assessed and common loading patterns were identified at different sites of the tibial plateau using an established numerical algorithm.ResultsThree regional patterns were found on the tibial plateau of intact knees. Following medial meniscectomy, the area of the first pattern which was located at the posterior aspect of the medial plateau was significantly reduced, while the magnitude of peak load was significantly increased by 120%. The second pattern which was located at the central-posterior aspects of the lateral plateau shifted anteriorly and laterally without changing its magnitude. The third pattern in the cartilage-to-cartilage contact region of the medial plateau was absent following meniscectomy. Meniscal transplantation largely restored the first pattern, but it did not restore the other two patterns.ConclusionThere are site-dependent changes in regional loading patterns on both the medial and lateral tibial plateau following medial meniscectomy. Even when a meniscal autograft is used where the geometry and material properties are kept constant, the only region in which the loading pattern is restored is at posterior aspect of the medial plateau.
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影响因子：
2.4
作者：
Cottrell, Jocelyn M.;Scholten, Paul;Maher, Suzanne A.
通讯作者：
Maher, Suzanne A.
内侧半月板同种异体移植后内侧胫骨平台的接触力学
影响因子：
4.8
作者：
Mohammad M. Alhalki;M. Hull;S. Howell
通讯作者：
S. Howell
同种异体半月板移植物：不同固定方法的生物力学后果
DOI：
--
发表时间：
2013
期刊：
影响因子：
--
作者：
Hongsheng Wang;Tony Chen;A. Gee;I. Hutchinson;K. Stoner;R. Warren;S. Maher
通讯作者：
S. Maher
影响因子：
7
作者：
D'Lima, DD;Hashimoto, S;Lotz, MK
通讯作者：
Lotz, MK
影响因子：
4.8
作者：
Alhalki, MM;Howell, SM;Hull, ML
通讯作者：
Hull, ML