Single-cell RNA Sequencing in Immunology.

Single-cell RNA Sequencing in Immunology.
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免疫学中的单细胞 RNA 测序

DOI:
10.2174/1389202921999201020203249
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发表时间:
2020-12
期刊:
影响因子:
2.6
通讯作者:
Yang C
Yang C
中科院分区:
生物学4区
文献类型:
--
作者:
Cao Y;Qiu Y;Tu G;Yang C

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复杂的免疫系统参与多种病理过程。单细胞RNA测序(scRNA-seq)能够分析准确到单个细胞和单个分子的复杂细胞混合物,因此有资格分析几种疾病的免疫反应。近年来,scRNA-seq技术在许多研究领域得到了广泛的应用,并取得了许多创新性的成果。本文就单细胞RNA测序技术在免疫学中的应用作一综述,并对未来的发展方向作一前景展望。
The complex immune system is involved in multiple pathological processes. Single-cell RNA sequencing (scRNA-seq) is able to analyze complex cell mixtures correct to a single cell and single molecule, thus is qualified to analyze immune reactions in several diseases. In recent years, scRNA-seq has been applied in many researching fields and has presented many innovative results. In this review, we intend to provide an overview of single-cell RNA sequencing applications in immunology and a prospect of future directions.
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