General method for regulating protein stability with light.
General method for regulating protein stability with light.
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DOI:
10.1021/cb400755b
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发表时间:
2014-01-17
影响因子:
4
通讯作者:
Wandless, Thomas J.
中科院分区:
文献类型:
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作者:
Bonger, Kimberly M.;Rakhit, Rishi;Payumo, Alexander Y.;Chen, James K.;Wandless, Thomas J.
Posttranslational regulation of protein abundance in cells is a powerful tool for studying protein function. We here describe a novel genetically encoded protein domain that is degraded upon exposure to non-toxic blue light. We demonstrate that fusion proteins containing this domain are rapidly degraded in cultured cells and in zebrafish upon illumination.
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影响因子:
48
作者:
Kennedy, Matthew J.;Hughes, Robert M.;Peteya, Leslie A.;Schwartz, Joel W.;Ehlers, Michael D.;Tucker, Chandra L.
通讯作者:
Tucker, Chandra L.
影响因子:
15
作者:
Polstein LR;Gersbach CA
通讯作者:
Gersbach CA
DOI:
10.1126/science.1159052
发表时间:
2008-10-17
期刊:
Science (New York, N.Y.)
影响因子:
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作者:
Lee J;Natarajan M;Nashine VC;Socolich M;Vo T;Russ WP;Benkovic SJ;Ranganathan R
通讯作者:
Ranganathan R
影响因子:
46.9
作者:
Yazawa, Masayuki;Sadaghiani, Amir M.;Dolmetsch, Ricardo E.
通讯作者:
Dolmetsch, Ricardo E.
DOI:
10.1038/nrmicro2622
发表时间:
2011-08-08
期刊:
Nature reviews. Microbiology
影响因子:
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作者:
通讯作者:
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