Common themes in the design and function of bacterial effectors.
Common themes in the design and function of bacterial effectors.
复制标题
细菌效应器设计和功能的常见主题。
DOI:
10.1016/j.chom.2009.04.008
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发表时间:
2009-06-18
影响因子:
30.3
通讯作者:
Galan, Jorge E.
中科院分区:
文献类型:
--
作者:
Galan, Jorge E.
Central to the biology of many pathogenic bacteria are a number of specialized machines, known as type III, type IV or type VI protein secretion systems. These machines have specifically evolved to deliver bacterial “effector” proteins into host cells with the capacity to modulate a variety of cellular functions. The identification of the biochemical activities of many effector proteins, coupled with a better understanding of their potential contribution to pathogenesis, have revealed common themes in the evolutionary design and function of these remarkable bacterial proteins.
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