Risk factors for mortality among 2009 A/H1N1 influenza hospitalizations in Maricopa County, Arizona, April 2009 to March 2010.
Risk factors for mortality among 2009 A/H1N1 influenza hospitalizations in Maricopa County, Arizona, April 2009 to March 2010.
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DOI：
10.1155/2012/914196
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发表时间：
2012
影响因子：
--
通讯作者：
Schumacher M
中科院分区：
文献类型：
--
作者：
Chowell G;Ayala A;Berisha V;Viboud C;Schumacher M
我们分析了2009年4月1日至2010年3月31日美国亚利桑那州马里科帕县公共卫生部加强监测系统中甲型h1n1流感住院病例的个人数据。我们还使用多变量logistic回归评估了甲型H1N1流感住院患者的死亡风险。印第安人的住院率明显更高(风险比(RR) = 6.2；95% CI: 6.15, 6.21)，非西班牙裔黑人（RR = 3.84; 95% CI: 3.8, 3.9）和西班牙裔（RR = 2.0; 95% CI: 2.0, 2.01）与非西班牙裔白人相比。整个春季，59.2%的住院患者接受了抗病毒治疗；治疗患者比例在下降期间显著增加至74.4%（卡方检验，P < 0.0001）。在我们的最佳拟合logistic模型中，与春季流行（2009年4月1日至2009年8月15日）相比，秋季流行（2009年8月16日至2010年3月31日，OR = 3.94; 95% CI: 1.72, 9.03） A/H1N1住院患者的调整后死亡风险显著更高。此外，慢性肺部疾病（OR = 3.5; 95%CI: 1.7, 7.4）、过去12个月内的癌症（OR = 4.3; 95%CI: 1.3, 14.8）、免疫抑制（OR = 4.0; 95%CI: 1.84, 8.9）和住院延误（OR = 4.6; 95%CI: 2.2, 9.5）与A/H1N1住院患者死亡风险增加显著相关。
We analyzed individual-level data on pandemic influenza A/H1N1pdm hospitalizations from the enhanced surveillance system of the Maricopa County Department of Public Health, AZ, USA from April 1st, 2009 to March 31st, 2010. We also assessed the the risk of death among A/H1N1 hospitalizations using multivariate logistic regression. Hospitalization rates were significantly higher among Native Americans (risk ratio (RR) = 6.2; 95% CI: 6.15, 6.21), non-Hispanic Black (RR = 3.84; 95% CI: 3.8, 3.9), and Hispanics (RR = 2.0; 95% CI: 2.0, 2.01) compared to non-Hispanic Whites. Throughout the spring, 59.2% of hospitalized patients received antiviral treatment; the proportion of patients treated increased significantly during the fall to 74.4% (Chi-square test, P < 0.0001). In our best-fit logistic model, the adjusted risk of death among A/H1N1 inpatients was significantly higher during the fall wave (August 16, 2009 to March 31, 2010, OR = 3.94; 95% CI: 1.72, 9.03) compared to the spring wave (April 1, 2009 to August 15, 2009). Moreover, chronic lung disease (OR = 3.5; 95% CI: 1.7, 7.4), cancer within the last 12 months (OR = 4.3; 95%CI: 1.3, 14.8), immuno-suppression (OR = 4.0; 95% CI: 1.84, 8.9), and admission delays (OR = 4.6; 95% CI: 2.2, 9.5) were significantly associated with an increased the risk of death among A/H1N1 inpatients.
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影响因子：
3.7
作者：
Higuera Iglesias AL;Kudo K;Manabe T;Corcho Berdugo AE;Corrales Baeza A;Alfaro Ramos L;Guevara Gutiérrez R;Manjarrez Zavala ME;Takasaki J;Izumi S;Bautista E;Perez Padilla JR
通讯作者：
Perez Padilla JR
影响因子：
11.8
作者：
Louie, Janice K.;Acosta, Meileen;Matyas, Bela T.
通讯作者：
Matyas, Bela T.
DOI：
10.1056/nejmopv0910738
发表时间：
2009-12-03
期刊：
The New England journal of medicine
影响因子：
--
作者：
Uyeki, Tim
通讯作者：
Uyeki, Tim
DOI：
10.1590/s1135-57272010000500008
发表时间：
2010-10-01
期刊：
Revista Española de Salud Pública
影响因子：
--
作者：
Santa-Olalla Peralta, Patricia;Cortes García, Marta;Sierra Moros, Mª José
通讯作者：
Sierra Moros, Mª José
影响因子：
3.7
作者：
Morgan OW;Bramley A;Fowlkes A;Freedman DS;Taylor TH;Gargiullo P;Belay B;Jain S;Cox C;Kamimoto L;Fiore A;Finelli L;Olsen SJ;Fry AM
通讯作者：
Fry AM