PPARγ in Monocytes: Less Pain, Any Gain?
PPARγ in Monocytes: Less Pain, Any Gain?
复制标题
单核细胞中的 PPARγ:减少痛苦,有收获吗?
DOI:
10.1016/s0092-8674(00)81567-6
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发表时间:
1998
期刊:
影响因子:
64.5
通讯作者:
B. Spiegelman
中科院分区:
文献类型:
--
作者:
B. Spiegelman
Introduction function for this receptor in these cells has been de-As the population of the US and other industrial counscribed. In the past few months, four papers have pretries ages and gets fatter, there is a more urgent need sented data suggesting that ligand activation of this to understand the molecular basis of obesity and those receptor powerfully regulates several aspects of monocommon and serious medical conditions clearly associcyte biology in ways that offer potential therapeutic ated with obesity: type II diabetes and cardiovascular promise and potential worries about side effects. disease. The cloning and identification of PPAR as a
DOI:
10.1056/nejm198904063201407
发表时间:
1989
期刊:
The New England journal of medicine
影响因子:
--
作者:
Steinberg,D;Parthasarathy,S;Carew,TE;Khoo,JC;Witztum,JL
通讯作者:
Witztum,JL