Size-selective pH-operated megagates on mesoporous silica materials.

Size-selective pH-operated megagates on mesoporous silica materials.
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尺寸选择性的pH训练列中列中二氧化硅材料。

DOI:
10.1039/c2nr32170j
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发表时间:
2012-12-07
期刊:
影响因子:
6.7
通讯作者:
Zink JI
Zink JI
中科院分区:
材料科学2区
文献类型:
--
作者:
Xue M;Cao D;Stoddart JF;Zink JI

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为了使介孔材料SBA-15机械化,已经在介孔二氧化硅材料SBA-15周围制备了pH响应的megagates。这些巨噬细胞在中性条件下保持封闭,但在pH 5时开放。巨晶的封端组分被设计成能够控制直径高达6.5 nm的孔。可通过使用不同的封盖组件来实现具有不同尺寸的有效载荷的选择性。通过能够监测有效载荷和帽的释放的时间分辨荧光光谱来证明兆栅极的操作。这项研究在可控释放领域开辟了新的可能性。
pH-responsive megagates have been fabricated around mesoporous silica material SBA-15 in order to mechanize the mesopores. These megagates remain closed in neutral conditions, but open at pH 5. The capping components of the megagates were designed to be capable of controlling pores up to 6.5 nm in diameter. Selectivity of payloads with different sizes can be achieved through the use of different capping components. The operation of the megagates was demonstrated by time-resolved fluorescence spectroscopy which is capable of monitoring the release of both the payload and the cap. This study opens up new possibilities in the field of controllable release.
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