Estimation of chronologic age using the aspartic acid racemization method. I. On human rib cartilage
Estimation of chronologic age using the aspartic acid racemization method. I. On human rib cartilage
复制标题
使用天冬氨酸外消旋法估计实际年龄。
DOI：
--
复制
发表时间：
2005
期刊：
影响因子：
--
通讯作者：
A. Teivens
中科院分区：
文献类型：
--
作者：
H. Pfeiffer;H. Mörnstad;A. Teivens
年龄测定在法医学中具有重要意义。目前，牙齿上的天冬氨酸外消旋化方法提供了成人个体的最佳手段之一。然而，如果牙齿不可用，则必须使用其他稳定的组织。在这项研究中，从肋骨软骨的适用性进行了测试。在尸检时从24名年龄为0.2-96岁的个体中获得肋软骨标本。制备酸溶性肽（SP）级分和不溶性胶原蛋白丰富（IC）级分，并使用HPLC技术测定D/L天冬氨酸的比例。D/L比值与年龄的相关系数SP为r = 0.91，IC为r = 0.97。因此，当牙齿不可用时，来自非负重区的软骨似乎是用天冬氨酸外消旋化方法估计年龄的有用组织来源。
Determinations of chronologic age are of great importance in forensic science. At present the aspartic acid racemization method on teeth provides one of the best means in adult individuals. However, if teeth are not available, some other stable tissue has to be used. In this study, the applicability of cartilage from the ribs has been tested. Specimens of rib cartilage were obtained at autopsy from 24 individuals aged 0.2–96 years. An acid-soluble peptide (SP) fraction and an insoluble collagen-rich (IC) fraction were prepared, and the ratio of D/L aspartic acid was determined using the HPLC technique. The correlation coefficient between the D/L ratio and age was r = 0.91 in SP and r = 0.97 in IC. It thus seems as if cartilage from non-weight-bearing areas may be a useful source of tissue for the estimation of chronologic age with the aspartic acid racemization method when teeth are not available.
影响因子：
15.9
作者：
SHAPIRO, SD;ENDICOTT, SK;CAMPBELL, EJ
通讯作者：
CAMPBELL, EJ
影响因子：
2.9
作者：
ASWAD, DW
通讯作者：
ASWAD, DW