HUMAN GRANULOSA CELLS CONTAIN INSULIN‐LIKE GROWTH FACTOR‐BINDING PROTEIN (IGF BP‐1) mRNA
HUMAN GRANULOSA CELLS CONTAIN INSULIN‐LIKE GROWTH FACTOR‐BINDING PROTEIN (IGF BP‐1) mRNA
复制标题
人颗粒细胞含有胰岛素样生长因子结合蛋白 (IGF BP-1) mRNA
作者:
R. Koistinen;A. Suikkari;A. Tiitinen;K. Kontula;M. Seppälä
Previous studies have demonstrated expression of insulin‐like growth factor‐binding protein (IGF BP‐1) in secretory and decidualized endometrium, in adult and fetal liver, and in HepG2 liver cancer cells. We have studied the expression of IGF BP‐1 in various types of ovarian neoplasias, normal ovary, and granulosa cells from hyperstimulated human ovarian follicles by RNA blot hybridization. A single 1.6 kb mRNA species, similar to that present in human decidua, was identified in poly(A)RNA‐containing preparations of granulosa cells and of a borderline malignant ovarian cystadenoma. This finding verifies the postulated production of IGF BP‐1 by the human ovary.
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DOI:
10.1161/01.hyp.0000027134.14160.1d
发表时间:
2002
期刊:
Hypertension (Dallas, Tex. : 1979)
影响因子:
--
作者:
Parhami-Seren,Behnaz;Haberly,Richard;Margolies,MichaelN;HaupertJr,GarnerT
通讯作者:
HaupertJr,GarnerT
DOI:
10.3109/10799898709054568
发表时间:
1987
期刊:
Journal of receptor research
影响因子:
--
作者:
Gates,GS;Bayer,S;Seibel,M;Poretsky,L;Flier,JS;Moses,AC
通讯作者:
Moses,AC
DOI:
10.1073/pnas.84.9.2643
发表时间:
1987-05
影响因子:
11.1
作者:
K. Ramasharma;C. Li
通讯作者:
K. Ramasharma;C. Li
DOI:
10.1210/mend-2-5-404
发表时间:
1988
期刊:
Molecular endocrinology (Baltimore, Md.)
影响因子:
--
作者:
Lee,YL;Hintz,RL;James,PM;Lee,PD;Shively,JE;Powell,DR
通讯作者:
Powell,DR
DOI:
10.1210/jcem-61-4-728
发表时间:
1985
期刊:
The Journal of clinical endocrinology and metabolism
影响因子:
--
作者:
Poretsky,L;Grigorescu,F;Seibel,M;Moses,AC;Flier,JS
通讯作者:
Flier,JS