Possible infectious causes in 651 patients with acute viral hepatitis during a 10-year period (1976-1985).

Possible infectious causes in 651 patients with acute viral hepatitis during a 10-year period (1976-1985).
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10 年期间(1976-1985 年)651 名急性病毒性肝炎患者的可能感染原因。

DOI:
10.1111/j.1600-0676.1987.tb00337.x
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发表时间:
2008
期刊:
Liver
影响因子:
--
通讯作者:
S. Furuta
S. Furuta
中科院分区:
--
文献类型:
--
作者:
K. Kiyosawa;Y. Gibo;T. Sodeyama;K. Furuta;H. Imai;H. Yoda;Y. Koike;K. Yoshizawa;S. Furuta

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1976年1月至1985年12月期间,对651名急性病毒性肝炎患者进行了血清学鉴定。其中,109名(17%)患有甲型肝炎,135名(21%)患有乙型肝炎,407名(62%)患有非甲非乙型肝炎。分析肝炎发病前6个月内发生病毒性肝炎的可能感染原因。大约 80% 的甲型肝炎病例和 70% 的乙型肝炎病例没有已知的危险因素,而在 67% 的非甲型、非乙型肝炎病例中记录了可能的感染危险因素。甲型肝炎的传染原因是摄入生贝类(11%)以及之前与甲型肝炎患者有家庭接触(10%)。对于乙型肝炎,危险因素包括医疗保险(24%),例如输血、外科手术、意外针刺和针灸以及性接触(6%)。对于非甲型、非乙型肝炎,最重要的感染原因是医疗操作(65%)。医院员工人数中,2 名(2%)患有甲型肝炎,15 名(11%)患有乙型肝炎,14 名(3%)患有非甲型、非乙型肝炎。这些数据表明,非甲型、非乙型肝炎可以是一种医院内疾病。
Six hundred and fifty-one patients with acute viral hepatitis were identified serologically between January 1976 and December 1985. Of these, 109 (17%) had hepatitis A, 135 (21%) had hepatitis B, and 407 (62%) had hepatitis non-A, non-B. The possible infectious causes for acquisition of viral hepatitis occurring within 6 months before the onset of hepatitis were analysed. Approximately 80% of cases of hepatitis A and 70% of hepatitis B had no known risk factor, while in 67% of cases of hepatitis non-A, non-B possible risk factors for infection were documented. Infectious causes for hepatitis A were ingestion of raw shellfish (11%) and previous familial contact with patients with hepatitis A (10%). For hepatitis B, risk factors included medicare (24%), such as transfusion, surgical operation, accidental needle stick and acupuncture, and sexual contact (6%). For hepatitis non-A, non-B, the most important infectious cause was medical procedures (65%). The numbers of hospital employees were 2 (2%) with hepatitis A, 15 (11%) with hepatitis B and 14 (3%) with hepatitis non-A, non-B. These data suggest that hepatitis non-A, non-B can be a kind of nosocomial disease.
DOI: 10.1093/infdis/145.6.886
发表时间: 1982-01-01
影响因子: 6.4
作者:
ALTER, MJ;GERETY, RJ;MATANOSKI, GM
通讯作者: MATANOSKI, GM