Ezh2 lines up the chromatin in T regulatory cells.
Ezh2 lines up the chromatin in T regulatory cells.
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DOI:
10.1016/j.immuni.2015.01.019
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发表时间:
2015-02-17
期刊:
影响因子:
32.4
通讯作者:
Kuchroo VK
中科院分区:
文献类型:
--
作者:
Wu C;Chen Z;Kuchroo VK
Epigenetic modulation is critical for regulating the development and function of T cells. In this issue of Immunity, show that the chromatin-modifying enzyme Ezh2 induced by CD28 costimulation is essential for regulatory T (Treg) cell maintenance during activation and differentiation.
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