Pathological processes and pretreatment cytologic diagnosis of neuroendocrine carcinoma of the endometrium: addendum report of the Kansai Clinical Oncology Group/Intergroup study in Japan
Pathological processes and pretreatment cytologic diagnosis of neuroendocrine carcinoma of the endometrium: addendum report of the Kansai Clinical Oncology Group/Intergroup study in Japan
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子宫内膜神经内分泌癌的病理过程和治疗前细胞学诊断：日本关西临床肿瘤学组/组间研究的附录报告
DOI：
10.1007/s00795-021-00288-4
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发表时间：
2021
影响因子：
1.8
通讯作者：
Teramoto Norihiro
中科院分区：
文献类型：
--
作者：
Matsumoto Harunobu;Nasu Kaei;Shikama Ayumi;Shiozaki Takaya;Futagami Masayuki;Kai Kentaro;Mori Taisuke;Yano Mitsutake;Yamada Takashi;Teramoto Norihiro
以前的一项回顾性研究的神经内分泌癌的子宫内膜，包括42例采用了中央病理审查，以确保结果的可靠性。然而，没有详细描述病理过程。在本研究中，我们进一步分析了这些过程和神经内分泌癌的预处理子宫内膜细胞学的结果。在本研究登记的18家机构的65例患者中，42例（64.6%）根据中心病理学审查诊断为子宫内膜神经内分泌癌。排除的23例中有13例与原诊断相矛盾：类腺癌5例（38.5%），未分化癌5例（38.5%），癌肉瘤3例（23.1%）。免疫组化染色导致13例中8例（61.5%）诊断改变。治疗前子宫内膜细胞学检查38例（90.5%），其中34例（89.5%）被发现，或怀疑，是积极的。为了确保选择适当的治疗方法并使患者正确知情，重要的是将神经内分泌癌与其他相似的组织学类型区分开来。子宫内膜细胞学检查可能有助于早期发现这种疾病。
A previous retrospective study of a neuroendocrine carcinoma of the endometrium including 42 cases employed a central pathologic review to ensure the reliability of the findings. However, the pathological processes were not described in detail. In this study, we further analyzed these processes and the results of pretreatment endometrial cytology of neuroendocrine carcinoma. Of the 65 patients from 18 institutions registered in the study, 42 (64.6%) were diagnosed with neuroendocrine carcinoma of the endometrium based on the central pathological review. Thirteen of the 23 excluded cases conflicted from their original diagnoses: 5 (38.5%) were diagnosed with endometrioid adenocarcinoma, 5 (38.5%) with undifferentiated carcinoma, and 3 (23.1%) with carcinosarcoma. Immunohistochemical staining led to a change in diagnosis for 8 (61.5%) of the 13 cases. Pretreatment endometrial cytology was examined in 38 (90.5%) cases; 34 (89.5%) of these 38 cases were found, or suspected, to be positive. To ensure the selection of appropriate therapy and keeping patients correctly informed, it is important to distinguish neuroendocrine carcinoma from other similar histologic types. Endometrial cytology may help in the early detection of this disease.
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DOI：
10.1007/bf01605139
发表时间：
1993-01-01
期刊：
VIRCHOWS ARCHIV A-PATHOLOGICAL ANATOMY AND HISTOPATHOLOGY
影响因子：
--
作者：
CHETTY, R;CLARK, SP;BHATHAL, PS
通讯作者：
BHATHAL, PS
影响因子：
3.5
作者：
Fujiwara, Hiroyuki;Takahashi, Yoshifumi;Suzuki, Mitsuaki
通讯作者：
Suzuki, Mitsuaki
DOI：
--
发表时间：
2008
期刊：
影响因子：
--
作者：
Noboru Manabe;Jyunpei Kimura
通讯作者：
Jyunpei Kimura
影响因子：
3.9
作者：
Matsumoto, Harunobu;Shimokawa, Mototsugu;Teramoto, Norihiro
通讯作者：
Teramoto, Norihiro
影响因子：
1.6
作者：
Matsumoto, Harunobu;Nasu, Kaei;Nishida, Haruto
通讯作者：
Nishida, Haruto