Visceral nociceptive afferent facilitates reaction of subnucleus reticularis dorsalis to acupoint stimulation in rats.
Visceral nociceptive afferent facilitates reaction of subnucleus reticularis dorsalis to acupoint stimulation in rats.
复制标题
内脏伤害性传入促进大鼠背网状亚核对穴位刺激的反应。
DOI：
10.1155/2013/931283
复制
发表时间：
2013
期刊：
影响因子：
--
通讯作者：
Chen R
中科院分区：
文献类型：
--
作者：
Li L;Yu L;Rong P;Ben H;Li X;Zhu B;Chen R
Objective.目的：探讨内脏器官病理状态下穴位面积及致敏性的变化。观察生理和病理条件下电针对网状背侧亚核（SRD）的量效变化。探讨穴位致敏的延髓机制。法将芥子油注入20只雄性SD大鼠的结肠和直肠，观察其对穴位致敏的影响。记录SRD神经元活动。内脏伤害性刺激由结肠直肠扩张（CRD）产生。观察电针“足三里-上巨虚”区治疗前后神经元活动的量效变化。组间比较采用配对t检验，P < 0.05为有统计学差异。结果.内脏炎症可促进穴位刺激引起的SRD神经元活动。内脏伤害性传入可增强神经元对穴位针刺的反应。电针引起的宽动态范围（WDR）神经元活动随内脏伤害性增加而增加。结论穴位的大小和功能与内脏器官的功能一致。穴位的敏感程度随脏腑功能失调而变化。
Objective. To explore the area and sensitization variance of acupoint when internal organs are under pathological condition. To observe quantity-effect variance of subnucleus reticularis dorsalis (SRD) to electroacupuncture under both physiological and pathological conditions. To explain medulla oblongata mechanism of acupoint sensitization. Method. Mustard oil was imported into colon and rectum of 20 male SD rats in order to observe its influence on acupoint sensitization. SRD neuron activity was recorded. Visceral nociceptive stimulus was generated by colorectal distension (CRD). Quantity-effect variance of neuron activity to electroacupuncture to “Zusanli-Shangjuxu” area both before and after CRD was observed. Paired t-test is used for cross-group comparison; P < 0.05 is deemed as of statistical differences. Result. Visceral inflammation could facilitate SRD neuron activity to acupoint stimulation. Visceral nociceptive afference could enhance neuron activity to acupoint acupuncture. Wide dynamic range (WDR) neuron activity caused by electroacupuncture increased when visceral nociception increased. Conclusion. The size and function of the acupoints comply with the functionality of the internal organs. The sensitive degree of acupoints changed according to malfunction of internal organs.
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影响因子：
7.4
作者：
NESS, TJ;METCALF, AM;GEBHART, GF
通讯作者：
GEBHART, GF
影响因子：
7.4
作者：
Verne, GN;Robinson, ME;Price, DD
通讯作者：
Price, DD
影响因子：
2.5
作者：
CERVERO, F;CONNELL, LA
通讯作者：
CONNELL, LA
影响因子：
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作者：
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通讯作者：
Cervero, F
影响因子：
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作者：
VILLANUEVA, L;BING, Z;LEBARS, D
通讯作者：
LEBARS, D