A Pilot Pre and Post 4 Week Intervention Evaluating the Effect of a Proprietary, Powdered, Plant Based Food on Micronutrient Status, Dietary Intake, and Markers of Health in a Healthy Adult Population.

A Pilot Pre and Post 4 Week Intervention Evaluating the Effect of a Proprietary, Powdered, Plant Based Food on Micronutrient Status, Dietary Intake, and Markers of Health in a Healthy Adult Population.
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DOI:
10.3389/fnut.2022.945622
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发表时间:
2022
影响因子:
5
通讯作者:
Pearson, Jeffrey P.
Pearson, Jeffrey P.
中科院分区:
农林科学2区
文献类型:
--
作者:
Wilcox, Matthew D.;Chater, Peter I.;Stanforth, Kyle J.;Williams, Rebecca;Brownlee, Iain A.;Pearson, Jeffrey P.

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世界卫生组织和国家公共卫生机构建议将“均衡、充足和多样的饮食”作为营养健康饮食的基础。HUEL是一种专有的、随时随地的粉状植物性食物,提供所有26种基本维生素和矿物质、蛋白质、必需脂肪、碳水化合物、纤维和植物营养素。通过对单独食用果胶粉进行为期4周的干预,评估单独食用果胶粉对微量营养素状况、饮食摄入量和健康指标的影响。通过一周的提前一周来评估习惯性能量摄入,健康的成年参与者(18岁或以上)记录他们的食物摄入量,之后只摄入Huel 4周。在干预前、后以及干预结束的一周内,对血样和身体成分进行评估。招募了30名参与者,其中20人(女性11人,中位年龄31岁,范围22-44岁)完成了研究,采集了19组血液样本。分析了22项血液指标,以及体重、BMI、腰围、内脏脂肪组织(VAT)和身体成分。除促甲状腺激素和胆碱外,所有血液微量营养素都被送往英国纽卡斯尔纽卡斯尔实验室的皇家维多利亚医院NHS进行分析。在研究过程中,有14项参数发生了显著变化,循环中的血红蛋白、铁、维生素B12和维生素D以及硒显著增加(p<0.05)。干预后糖化血红蛋白、总胆固醇和非高密度脂蛋白胆固醇、维生素A和维生素E、钾、体重指数、增值税和腰围均显著降低(p<0.05)。虽然能量摄入量在干预期间有所下降,但通过饮食总依从性分数量化的推荐微量营养素摄入量的依从性显著增加,这与微量营养素状态的保持或改善相一致。这项研究潜在地表明,只摄入Huel 4周并不会对微量营养素状况产生负面影响。
A “balanced, adequate, and varied diet” is recommended as the basis of nutritionally sound diet by the World Health Organisation and national public health agencies. Huel is a proprietary, on-the-go, powdered, plant based food, providing all 26 essential vitamins and minerals, protein, essential fats, carbohydrate, fibre, and phytonutrients. Assessing the effect of solely consuming Huel on micronutrient status, dietary intake and markers of health was achieved through a 4-week intervention of solely Huel powder. Habitual energy intake was assessed through a one-week lead in period with healthy adult participants (aged 18 or over) logging their food intake, after which only Huel was consumed for 4 weeks. Blood samples and body composition was assessed before and after the lead in week as well the end of the intervention. Thirty participants were recruited with 20 (11 females, median age 31, range 22–44) completing the study, 19 sets of blood samples were collected. 22 blood markers were analysed along with weight, BMI, waist circumference, visceral adipose tissue (VAT), and body composition. All blood micronutrients, except for Thyroid Stimulating Hormone and choline were sent to Royal Victoria Infirmary NHS, Newcastle Laboratory (Newcastle upon Tyne, United Kingdom) for analysis. Fourteen of the parameters significantly changed over the course of the study with circulating haemoglobin, iron, vitamins B12 and D as well as selenium significantly increasing (p < 0.05). HbA1c, total and non-HDL cholesterol, vitamins A and E, potassium, BMI, VAT, and waist circumference all significantly decreased (p < 0.05) post intervention. Although energy intake decreased during the intervention period, the adherence to recommended micronutrient intake, as quantified by the dietary Total Adherence Score, significantly increased which tallies with the preservation or improvement of micronutrient status. This study potentially demonstrates that consuming only Huel for 4 weeks does not negatively affect micronutrient status.
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