Regulating Il9 transcription in T helper cells.
Regulating Il9 transcription in T helper cells.
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DOI:
10.1016/j.it.2011.01.006
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发表时间:
2011-04
影响因子:
16.8
通讯作者:
Kaplan MH
中科院分区:
文献类型:
--
作者:
Perumal NB;Kaplan MH
T helper cells are critical for the development of immunity to infections and inflammatory disease. The acquisition of specific cytokine-secreting profiles, primed by the cytokine microenvironment, is required for effector function of Th cells. The most recent addition to the growing list of effector subsets are Th9 cells that secrete IL-9. In this article we propose a model for the transcriptional regulation of the Il9 gene in IL-9-expressing T cells and the relatedness of this subset to other Th phenotypes. We suggest that transcription factors restricted to certain Th subsets, and common among several subsets, may play a role in the plasticity of Th9 cells.
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影响因子:
64.5
作者:
Ivanov, Ivaylo I.;McKenzie, Brent S.;Littman, Dan R.
通讯作者:
Littman, Dan R.
DOI:
10.1084/jem.20070663
发表时间:
2007-08-06
期刊:
The Journal of experimental medicine
影响因子:
--
作者:
Annunziato F;Cosmi L;Santarlasci V;Maggi L;Liotta F;Mazzinghi B;Parente E;Filì L;Ferri S;Frosali F;Giudici F;Romagnani P;Parronchi P;Tonelli F;Maggi E;Romagnani S
通讯作者:
Romagnani S
DOI:
10.4049/jimmunol.1003049
发表时间:
2011-03-15
期刊:
Journal of immunology (Baltimore, Md. : 1950)
影响因子:
--
作者:
Goswami R;Kaplan MH
通讯作者:
Kaplan MH
影响因子:
14.2
作者:
Cosmi, Lorenzo;Maggi, Laura;Annunziato, Francesco
通讯作者:
Annunziato, Francesco
影响因子:
32.4
作者:
Hegazy, Ahmed N.;Peine, Michael;Loehning, Max
通讯作者:
Loehning, Max