An estimate of asthma prevalence in Africa: a systematic analysis.
An estimate of asthma prevalence in Africa: a systematic analysis.
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DOI：
10.3325/cmj.2013.54.519
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发表时间：
2013-12
影响因子：
1.9
通讯作者：
Campbell H
中科院分区：
文献类型：
--
作者：
Adeloye D;Chan KY;Rudan I;Campbell H
估计和比较1990年、2000年和2010年非洲哮喘患病率，以提供有助于规划对该疾病的公共卫生应对的信息。我们对Medline、EMBASE和Global Health进行了系统检索，以查找1990年至2012年期间发表的哮喘研究。我们纳入了基于横断面人群的研究，提供了哮喘患病率的数值估计。我们计算了加权平均患病率，并应用了一个流行病学模型，将年龄与哮喘患病率联系起来。联合国1990年、2000年和2010年的非洲人口数据被用来估计哮喘病例。我们的搜索返回了790项研究。我们保留了45项符合我们选择标准的研究。1990年在非洲，我们估计有3410万哮喘病例（12.1%; 95%置信区间[CI] 7.2-16.9）15岁以下儿童，6，490万在年龄<45岁的人群中（11.8%; 95% CI 7.9-15.8），在总人口中为7440万（11.7%; 95% CI 8.2-15.3）。2000年，我们估计15岁以下儿童中有4130万例（12.9%; 95%CI 8.7-17.0），45岁以下人群中有8240万例（12.5%; 95%CI 5.9-19.1），总人口中有9480万例（12.0%; 95%CI 5.0-18.8）。2010年，15岁以下儿童的死亡人数增至4 970万人（13.9%; 95% CI 9.6-18.3），45岁以下人口增至1.029亿人（13.8%; 95% CI 6.2-21.4），总人口增至1.193亿人（12.8%; 95% CI 8.2-17.1）。在通过书面和视频问卷调查确定病例的研究中，哮喘患病率没有显著差异。然而，城市居民的哮喘病粗发病率始终高于农村居民。我们的研究结果表明，在过去的二十年里，非洲哮喘的患病率不断上升。由于缺乏数据，我们认为哮喘的真实患病率可能仍然被低估。非洲各国政府有必要考虑这种日益增加的疾病负担的影响，并调查城市化加剧和人口老龄化等潜在风险因素在其应对这一挑战的政策和卫生规划中的相对重要性。
To estimate and compare asthma prevalence in Africa in 1990, 2000, and 2010 in order to provide information that will help inform the planning of the public health response to the disease. We conducted a systematic search of Medline, EMBASE, and Global Health for studies on asthma published between 1990 and 2012. We included cross-sectional population based studies providing numerical estimates on the prevalence of asthma. We calculated weighted mean prevalence and applied an epidemiological model linking age with the prevalence of asthma. The UN population figures for Africa for 1990, 2000, and 2010 were used to estimate the cases of asthma, each for the respective year. Our search returned 790 studies. We retained 45 studies that met our selection criteria. In Africa in 1990, we estimated 34.1 million asthma cases (12.1%; 95% confidence interval [CI] 7.2-16.9) among children <15 years, 64.9 million (11.8%; 95% CI 7.9-15.8) among people aged <45 years, and 74.4 million (11.7%; 95% CI 8.2-15.3) in the total population. In 2000, we estimated 41.3 million cases (12.9%; 95% CI 8.7-17.0) among children <15 years, 82.4 million (12.5%; 95% CI 5.9-19.1) among people aged <45 years, and 94.8 million (12.0%; 95% CI 5.0-18.8) in the total population. This increased to 49.7 million (13.9%; 95% CI 9.6-18.3) among children <15 years, 102.9 million (13.8%; 95% CI 6.2-21.4) among people aged <45 years, and 119.3 million (12.8%; 95% CI 8.2-17.1) in the total population in 2010. There were no significant differences between asthma prevalence in studies which ascertained cases by written and video questionnaires. Crude prevalences of asthma were, however, consistently higher among urban than rural dwellers. Our findings suggest an increasing prevalence of asthma in Africa over the past two decades. Due to the paucity of data, we believe that the true prevalence of asthma may still be under-estimated. There is a need for national governments in Africa to consider the implications of this increasing disease burden and to investigate the relative importance of underlying risk factors such as rising urbanization and population aging in their policy and health planning responses to this challenge.
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影响因子：
3.1
作者：
Bahadori, Katayoun;Doyle-Waters, Mary M;FitzGerald, J Mark
通讯作者：
FitzGerald, J Mark
影响因子：
2.8
作者：
Cazzoletti, Lucia;Marcon, Alessandro;de Marco, Roberto
通讯作者：
de Marco, Roberto
影响因子：
14.2
作者：
Bousquet, Jean;Mantzouranis, Eva;Zuberbier, Torsten
通讯作者：
Zuberbier, Torsten
影响因子：
12.4
作者：
Ait-Khaled, N.;Odhiambo, J.;Zar, H. J.
通讯作者：
Zar, H. J.
影响因子：
168.9
作者：
Beaglehole, Robert;Bonita, Ruth;Watt, Judith
通讯作者：
Watt, Judith