Bacterial colonization and succession in a newly opened hospital.
Bacterial colonization and succession in a newly opened hospital.
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DOI：
10.1126/scitranslmed.aah6500
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发表时间：
2017-05-24
影响因子：
17.1
通讯作者：
Gilbert JA
中科院分区：
文献类型：
--
作者：
Lax S;Sangwan N;Smith D;Larsen P;Handley KM;Richardson M;Guyton K;Krezalek M;Shogan BD;Defazio J;Flemming I;Shakhsheer B;Weber S;Landon E;Garcia-Houchins S;Siegel J;Alverdy J;Knight R;Stephens B;Gilbert JA
栖息在医院的微生物可能会显着影响患者的恢复率和结果（参考文献）。为了在社区层面了解微生物如何在医院环境中定植和移动，我们在一年的时间里绘制了医院表面，空气和水之间的微生物动力学，以患者和工作人员作为新医院投入运营。在引入工作人员和患者后，医院微生物组立即被人类皮肤相关细菌所主导。人类皮肤样本的微生物多样性最低，而与户外环境相互作用的表面上的多样性最大。患者房间表面的微生物群，特别是床栏杆，始终与当前患者的皮肤微生物群落相似，相似程度与较高的湿度和较低的温度显著相关。工作人员之间的微生物相似性表现出显着的季节性趋势是最大的夏末/初秋与湿度增加。
The microorganisms that inhabit hospitals may significantly influence patient recovery rates and outcomes (REFs). To develop a community level understating of how microorganisms colonize and move through the hospital environment, we mapped microbial dynamics between hospital surfaces, air and water to patients and staff over the course of one year as a new hospital became operational. Immediately following the introduction of staff and patients, the hospital microbiome became dominated by human skin-associated bacteria. Human skin samples had the lowest microbial diversity, while the greatest diversity was found on surfaces interacting with outdoor environments. The microbiota of patient room surfaces, especially bedrails, consistently resembled the skin microbial community of the current patient, with degree of similarity significantly correlated to higher humidity and lower temperatures. Microbial similarity between staff members showed a significant seasonal trend being greatest in late summer/early fall correlating with increased humidity.
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DOI：
10.1038/ismej.2012.8
发表时间：
2012-08
期刊：
The ISME journal
影响因子：
--
作者：
通讯作者：
--
DOI：
10.1073/pnas.1310750111
发表时间：
2014-01-14
影响因子：
11.1
作者：
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通讯作者：
Lynch, Susan V.
影响因子：
7.4
作者：
Dedesko, Sandra;Stephens, Brent;Siegel, Jeffrey A.
通讯作者：
Siegel, Jeffrey A.
影响因子：
2.7
作者：
Kang DD;Froula J;Egan R;Wang Z
通讯作者：
Wang Z
影响因子：
5.9
作者：
FAITH, DP
通讯作者：
FAITH, DP