Longitudinal network re-organization across learning and development.
Longitudinal network re-organization across learning and development.
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DOI：
10.1016/j.neuroimage.2021.117784
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发表时间：
2021-04-01
期刊：
影响因子：
5.7
通讯作者：
Telzer EH
中科院分区：
文献类型：
--
作者：
McCormick EM;Peters S;Crone EA;Telzer EH
虽然我们很清楚大脑在短期经验/学习和长期发展中经历了变化，但尚不清楚这两种机制如何相互作用以产生发展结果。在这里，我们测试了一种学习和发展的互动模型，其中某些与学习相关的变化受到大脑发育变化的限制，而另一种发展即实践模型则主要由经验积累决定，而不受年龄的影响。参与者（8-29岁）参加了一项三波加速纵向研究，在此期间，他们在fMRI扫描期间完成了反馈学习任务。采用一种新颖的纵向建模方法，我们探讨了学习、经验和发展同时对任务过程中行为表现和网络模块化的独特和调节作用。我们发现了行为和大脑发展的非线性模式，并且相对于naïve受试者，更多的经验支持增加的学习和网络模块化。我们还发现，在整个青少年发展过程中，大脑-行为关系的变化，其中网络模块化的增强预示着学习能力的提高，但仅在从青春期过渡到成年早期之后。这些结果为经验和发展的互动观点提供了令人信服的支持，即大脑的变化以基于发展目标的特定情境的方式影响行为。
While it is well understood that the brain experiences changes across short-term experience/learning and long-term development, it is unclear how these two mechanisms interact to produce developmental outcomes. Here we test an interactive model of learning and development where certain learning-related changes are constrained by developmental changes in the brain against an alternative development-as-practice model where outcomes are determined primarily by the accumulation of experience regardless of age. Participants (8–29 years) participated in a three-wave, accelerated longitudinal study during which they completed a feedback learning task during an fMRI scan. Adopting a novel longitudinal modeling approach, we probed the unique and moderated effects of learning, experience, and development simultaneously on behavioral performance and network modularity during the task. We found nonlinear patterns of development for both behavior and brain, and that greater experience supported increased learning and network modularity relative to naïve subjects. We also found changing brain-behavior relationships across adolescent development, where heightened network modularity predicted improved learning, but only following the transition from adolescence to young adulthood. These results present compelling support for an interactive view of experience and development, where changes in the brain impact behavior in context-specific fashion based on developmental goals.
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影响因子：
4.3
作者：
Ellefsen KO;Mouret JB;Clune J
通讯作者：
Clune J
影响因子：
4.7
作者：
Johnson, Carolyn;Wilbrecht, Linda
通讯作者：
Wilbrecht, Linda
影响因子：
64.8
作者：
Daw, Nathaniel D.;O'Doherty, John P.;Dayan, Peter;Seymour, Ben;Dolan, Raymond J.
通讯作者：
Dolan, Raymond J.
DOI：
10.1080/10705510802154349
发表时间：
2008-07-01
影响因子：
6
作者：
Flora, David B.
通讯作者：
Flora, David B.
DOI：
10.1207/s15328007sem0802_2
发表时间：
2001-01-01
影响因子：
6
作者：
Li, Fuzhong;Duncan, Terry E.;Hops, Hyman
通讯作者：
Hops, Hyman