Preclinical models for investigating how bone marrow adipocytes influence bone and hematopoietic cellularity.
Preclinical models for investigating how bone marrow adipocytes influence bone and hematopoietic cellularity.
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DOI:
10.1016/j.beem.2021.101547
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发表时间:
2021-07
期刊:
影响因子:
--
通讯作者:
MacDougald OA
中科院分区:
文献类型:
--
作者:
Li Z;MacDougald OA
Laboratory mice are a crucial preclinical model system for investigating BMAd-bone and BMAd-hematopoiesis interactions. In this review, we evaluate the suitability of mice to model common human diseases related to osteopenia or hematopoietic disorders, pointing out consistencies and discrepancies among different studies, and provide insights into model selection. Species, age, sex, skeletal site, and treatment protocol should all be considered when designing future studies.
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影响因子:
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DOI:
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BONE AND MINERAL
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10.1530/joe-15-0473
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The Journal of endocrinology
影响因子:
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作者:
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通讯作者:
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5.6
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