Demand curve analysis of marijuana use among persons living with HIV.

Demand curve analysis of marijuana use among persons living with HIV.
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DOI:
10.1016/j.drugalcdep.2021.108524
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发表时间:
2021-03-01
影响因子:
4.2
通讯作者:
Lundahl LH
Lundahl LH
中科院分区:
医学2区
文献类型:
--
作者:
Greenwald MK;Sarvepalli SS;Cohn JA;Lundahl LH

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尽管大麻使用的医疗化和合法化,但影响艾滋病毒感染者(PLWH)对大麻需求的因素尚不完全清楚。这种知识差距破坏了有效的临床管理和政策。本研究使用需求曲线模拟方法来解决这些问题。使用大麻的PLWH(N=119)完成了实验任务,以模拟不同成本(金钱或时间)的大麻购买/使用量,以及转售大麻或大麻治疗用途登记卡与利润的可能性。其他模拟评估了大麻相对于其他毒品和非毒品商品的购买情况。随着金钱和时间成本的增加,模拟大麻的使用减少了。对于更严重的大麻使用障碍(CUD)和焦虑,中间疼痛水平和过去90天阿片类药物使用的参与者,消费量更大。虽然很少有参与者选择出售他们的登记卡,大麻转售(转移)急剧增加的利润。寻求大麻治疗使用认证的可能性与注册卡费用有关,必须访问更多的医生才能获得签名,并且延迟收到卡,并且随着认证的持续时间而增加。报告最近使用阿片类药物的参与者更有可能寻求认证。评估的几种商品的消费与大麻无关。模拟大麻使用与参与者的临床特征(CUD,焦虑和疼痛症状,最近的阿片类药物使用)有关,与购买其他商品无关。寻求大麻治疗用途注册的可能性受到几种类型的成本和最近阿片类药物使用的影响。与会者不大可能挪用登记卡。我们讨论了这些发现的临床和政策含义。
Despite medicalization and legalization of marijuana use, factors influencing demand for marijuana among persons living with HIV (PLWH) are incompletely understood. This knowledge gap undermines effective clinical management and policies. This study used demand curve simulation methods to address these issues. Marijuana-using PLWH (N=119) completed experimental tasks to simulate amount of marijuana purchasing/use across different costs (money or time), and likelihood of reselling marijuana or marijuana therapeutic-use registration card in relation to profits. Additional simulations assessed purchasing of marijuana relative to other drug and non-drug goods. Simulated marijuana use decreased as money and time costs increased. Consumption was greater for participants with more severe Cannabis Use Disorder (CUD) and anxiety, intermediate pain levels, and past 90-day opioid use. Whereas few participants chose to sell their registration card, marijuana resale (diversion) steeply increased with profit. Likelihood of seeking marijuana therapeutic-use certification decreased in relation to registration card money cost, having to visit more physicians to get a signature, and delay to receiving the card, and increased with duration of certification. Participants who reported recent opioid use were more likely to seek certification. Consumption of several commodities assessed was independent of marijuana. Simulated marijuana use was related to participants’ clinical profile (CUD, anxiety and pain symptoms, recent opioid use), and unrelated to purchasing other goods. Likelihood of seeking marijuana therapeutic-use registration was affected by several types of costs and recent opioid use. Participants were unlikely to divert registration cards. We discuss clinical and policy implications of these findings.
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