Physical and mental impact of psoriasis severity as measured by the compact Short Form-12 Health Survey (SF-12) quality of life tool.

Physical and mental impact of psoriasis severity as measured by the compact Short Form-12 Health Survey (SF-12) quality of life tool.
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DOI:
10.1038/jid.2011.427
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发表时间:
2012-04
影响因子:
6.5
通讯作者:
Korman, Neil J.
Korman, Neil J.
中科院分区:
医学1区
文献类型:
--
作者:
Grozdev, Ivan;Kast, Douglas;Gao, Lauren;Carlson, Diana;Pujari, Prasad;Schmotzer, Brian;Babineau, Denise;Kern, Elizabeth;McCormick, Thomas;Cooper, Kevin D.;Korman, Neil J.

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简明健康调查表(SF-12)用于使用身体健康评分(PCS)和心理健康评分(MCS)评估患者的生活质量(QoL)。本研究的目的是确定SF-12 PCS和MCS是否与银屑病严重程度相关,并比较Murdough银屑病家庭中心(MFCP)患者和全国功能健康状况调查数据中包含的其他主要慢性疾病患者的QoL。我们使用了参加MFCP的429名成年患者的数据。在完成SF-12问卷时,使用银屑病面积严重程度指数(PASI)评估银屑病严重程度。其他变量包括年龄、性别、体重指数、银屑病关节炎、精神疾病和合并症。使用线性回归模型估计效应量±95%置信区间。PASI每增加10分,MCS减少1.1±1.3个单位(P = 0.100),PCS减少2.4±1.3个单位(P<0.001)。在调整变量后,银屑病严重程度与PCS和MCS相关,尽管在某些模型中这种关系的强度减弱。银屑病严重程度与QoL降低相关。SF-12可能是评估银屑病患者生活质量的有用工具。
The Short Form-12 Health Survey (SF-12) is used to assess the patient’s quality of life (QoL) using the physical component score (PCS) and the mental component score (MCS). The purpose of this study was to determine whether the SF-12 PCS and MCS are associated with psoriasis severity and to compare QoL between Murdough Family Center for Psoriasis (MFCP) patients and patients with other major chronic diseases included in the National Survey of Functional Health Status data. We used data from 429 adult patients enrolled in MFCP. Psoriasis Area Severity Index (PASI) was used to assess psoriasis severity at the time of completion of the SF-12 questionnaire. Other variables included age, sex, body mass index, psoriatic arthritis, psychiatric disorders, and comorbidities. Linear regression models were used to estimate effect sizes ±95% confidence intervals. For every 10-point increase in PASI, there was a 1.1±1.3 unit decrease in MCS (P = 0.100) and a 2.4±1.3 unit decrease in PCS (P<0.001). Psoriasis severity was associated with PCS and MCS after adjusting for variables, although the strength of the relationship was attenuated in some models. Psoriasis severity is associated with decreased QoL. SF-12 may be a useful tool for assessing QoL among psoriasis patients.
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