Effect of age on mechanical properties of the collagen phase in different orientations of human cortical bone.
Effect of age on mechanical properties of the collagen phase in different orientations of human cortical bone.
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DOI：
10.1016/j.bone.2013.04.006
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发表时间：
2013-08
期刊：
影响因子：
4.1
通讯作者：
Wang, Xiaodu
中科院分区：
文献类型：
--
作者：
Leng, Huijie;Reyes, Michael J.;Dong, Xuanliang N.;Wang, Xiaodu
胶原相在皮质骨的力学行为中起着重要的作用。然而，老化对胶原相的机械行为的影响仍然知之甚少。在这项研究中，对年轻，中年和老年供体的脱矿人皮质骨样品进行微拉伸试验，并检查不同方向（即骨的纵向和横向）的胶原相的机械性能的老化效应。本研究的结果表明，弹性模量和极限强度的脱钙骨标本的老化下降，在纵向和横向方向。然而，无论是否老化，失效应变在两个方向上均未显示出显著变化。这些结果表明，骨中胶原相的刚度和强度随着纵向和横向方向上的老化而劣化。然而，在纵向和横向方向上的胶原相的失效应变中没有反映出老化效应，这意味着胶原相的最大可持续变形与老化和方向无关。
The collagen phase plays an important role in mechanical behaviors of cortical bone. However, aging effects on the mechanical behavior of the collagen phase is still poorly understood. In this study, micro-tensile tests were performed on demineralized human cortical bone samples from young, middle-aged, and elderly donors and aging effects on the mechanical properties of the collagen phase in different orientations (i.e. longitudinal and transverse directions of bone) were examined. The results of this study indicated that the elastic modulus and ultimate strength of the demineralized bone specimens decreased with aging in both the longitudinal and transverse orientations. However, the failure strain exhibited no significant changes in both orientations regardless of aging. These results suggest that the stiffness and strength of the collagen phase in bone are deteriorated with aging in both longitudinal and transverse directions. However, the aging effect is not reflected in the failure strain of the collagen phase in both longitudinal and transverse orientations, implying that the maximum sustainable deformation of the collagen phase is independent of aging and orientation.
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影响因子：
2.4
作者：
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发表时间：
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影响因子：
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