Diagnosing PD-MCI by MDS Task Force criteria: how many and which neuropsychological tests?

Diagnosing PD-MCI by MDS Task Force criteria: how many and which neuropsychological tests?
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DOI:
10.1002/mds.26084
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发表时间:
2015-03
期刊:
影响因子:
8.6
通讯作者:
Stebbins, Glenn T.
Stebbins, Glenn T.
中科院分区:
医学1区
文献类型:
--
作者:
Goldman, Jennifer G.;Holden, Samantha;Ouyang, Bichun;Bernard, Bryan;Goetz, Christopher G.;Stebbins, Glenn T.

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根据运动障碍协会 (MDS) 工作组标准确定帕金森病轻度认知障碍 (PD-MCI) 的综合(II 级)神经心理学电池的最佳特性仍未解决。 76 名非痴呆 PD 患者使用共识诊断和 II 级标准进行了 PD-MCI 分类。我们检查了五个指定认知领域中每个领域的最佳测试数量,确定了每个领域内的最佳测试,并确定了 PD-MCI II 级诊断的最佳整体组合。每个域进行两次测试的电池提供了高度实用、稳健的诊断评估。使用两项最佳测试和定义为低于正常值 2 个标准差的损伤的 II 级测试对于 PD-MCI 诊断具有高度敏感性和特异性。我们的研究结果强烈支持 MDS 特别工作组 II 级测试建议,为创建用于 PD-MCI 诊断的最佳、高效神经心理学测试组提供了框架,并提供了具体的测试建议。
The optimal properties of a comprehensive (Level II) neuropsychological battery for determining Parkinson’s disease mild cognitive impairment (PD-MCI) by Movement Disorder Society (MDS) Task Force criteria remain unresolved. Seventy-six non-demented PD patients underwent PD-MCI classification using a consensus diagnosis and Level II criteria. We examined the optimal number of tests in each of the five designated cognitive domains, identified the best tests within each domain, and determined the best overall battery for PD-MCI Level II diagnosis. A battery with two tests per domain provided a highly practical, robust diagnostic assessment. Level II testing with the two best tests and impairment defined as 2 standard deviations below norms was highly sensitive and specific for PD-MCI diagnosis. Our findings strongly support the MDS Task Force Level II testing recommendations, provide a framework for creating an optimal, efficient neuropsychological test battery for PD-MCI diagnosis, and offer specific test recommendations.
DOI: 10.1002/mds.25062
发表时间: 2012-08
期刊: Movement disorders : official journal of the Movement Disorder Society
影响因子: --
作者:
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DOI: 10.1016/j.parkreldis.2013.05.006
发表时间: 2013-09
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DOI: 10.1001/archneur.1978.00500300038006
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DOI: 10.1002/mds.25655
发表时间: 2013-12-01
期刊: MOVEMENT DISORDERS
影响因子: 8.6
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发表时间: 2013-05
期刊: Movement disorders : official journal of the Movement Disorder Society
影响因子: --
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