Resolving intralocus sexual conflict: genetic mechanisms and time frame.

Resolving intralocus sexual conflict: genetic mechanisms and time frame.
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解决座内性冲突:遗传机制和时间框架。

DOI:
10.1093/jhered/esq011
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发表时间:
2010
期刊:
The Journal of heredity
影响因子:
--
通讯作者:
Rice,WilliamR
Rice,WilliamR
中科院分区:
--
文献类型:
--
作者:
Stewart,AndrewD;Pischedda,Alison;Rice,WilliamR

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室内性冲突的发生是由于性拮抗等位基因的表达:这些等位基因在一个性别中表达时提高了适合度,而在另一个性别中表达时降低了适合度。当一种性状在两性间具有正的遗传相关性时,两性被选择到不同的表型最佳时,这种遗传冲突就在所难免。在这里,我们综合了基因组学、微阵列分析、发育和分子遗传学等领域的最新发展,以建立可行的机制,通过这些机制可以减少两性间遗传相关性,以及冲突解决的时间进程。
Intralocus sexual conflict occurs due to the expression of sexually antagonistic alleles: those that increase fitness when expressed in one sex but decrease fitness when expressed in the other sex. This genetic conflict is expected whenever the sexes are selected toward differing phenotypic optima for a trait that has a positive genetic correlation between the sexes. Here we synthesize recent developments in the areas of genomics, microarray analysis, and developmental and molecular genetics to establish feasible mechanisms by which the intersexual genetic correlation can be reduced, as well as the time course over which conflict resolution is expected to evolve.
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