Objectively measured physical activity is related to cognitive function in older adults.

Objectively measured physical activity is related to cognitive function in older adults.
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DOI:
10.1111/jgs.12524
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发表时间:
2013-11
影响因子:
6.3
通讯作者:
Crist K
Crist K
中科院分区:
医学1区
文献类型:
--
作者:
Kerr J;Marshall SJ;Patterson RE;Marinac CR;Natarajan L;Rosenberg D;Wasilenko K;Crist K

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探讨自由生活的老年人认知功能与不同强度体力活动 (PA) 所花费的时间之间的关系。对参加持续护理退休社区随机对照试验组的参与者进行横断面分析。居住在圣地亚哥县 7 个持续护理退休社区的 215 名老年人:平均年龄 83 岁,70% 为女性,35% 受过研究生教育。 PA 通过髋部佩戴的加速度计进行客观测量,数据汇总到分钟级别。使用三个切点来评估低光、高光和中强光强度 PA (MVPA)。完成试验 A 和 B,并使用每次测试的时间(秒)和测试 B 减去 A 的时间(秒)作为认知功能的测量。对变量进行对数转换并输入线性回归模型,调整人口因素(年龄、教育、性别)和其他 PA 强度变量。低光 PA 与任何 Trails 测试分数均无关。高光 PA 与轨迹 A、B 和 B-minus-A 显着相关;但仅限于未调整的模型。在调整人口统计变量后,MVPA 与轨迹 B 和 B-减-A 相关。这些数据表明老年人的 PA 强度和认知功能之间可能存在剂量反应。支持 MVPA 与认知功能之间关系的更强有力的发现与之前的观察和干预研究一致。
To explore the relationship between cognitive functioning and the time spent at different intensities of physical activity (PA) in free-living older adults. Cross sectional analyses of participants enrolled in a randomized controlled trial set in continuing care retirement communities. 215 older adults residing in 7 continuing care retirement communities in San Diego County: average age 83 years, 70% female and 35% with graduate level education. PA was measured objectively by hip worn accelerometers with data aggregated to the minute level. Three cut points were used to assess low-light, high-light, and moderate-to-vigorous intensity PA (MVPA). Trail Making Tests A and B were completed and time for each test (sec) and test B-minus- A time (sec) were used as measures of cognitive functioning. Variables were log transformed and entered into linear regression models adjusting for demographic factors (age, education, gender) and other PA intensity variables. Low-light PA was not related to any Trails test score. High-light PA was significantly related to Trails A, B and B-minus-A; but only in unadjusted models. MVPA was related to Trails B and B-minus-A after adjusting for demographic variables. These data suggest there may be a dose response between PA intensity and cognitive functioning in older adults. The stronger findings supporting a relationship between MVPA and cognitive functioning are consistent with previous observational and intervention studies.
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