Prevalence and correlates of chronic fatigue syndrome and post-traumatic stress disorder after the outbreak of the COVID-19.
Prevalence and correlates of chronic fatigue syndrome and post-traumatic stress disorder after the outbreak of the COVID-19.
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DOI：
10.1007/s13365-021-00949-1
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发表时间：
2021-03
影响因子：
3.2
通讯作者：
Pakdaman H
中科院分区：
文献类型：
--
作者：
Simani L;Ramezani M;Darazam IA;Sagharichi M;Aalipour MA;Ghorbani F;Pakdaman H
随着SARS-COV-2成为全球大流行，许多研究人员对COVID-19的长期并发症表示担忧。慢性疲劳综合征/肌痛性脑脊髓炎（CFS/ME）是一种持续性、使人衰弱和原因不明的疲劳性疾病。我们调查了COVID-19幸存者6个月以上的心理疾病，如CFS和创伤后应激障碍（PTSD）。所有来自伊朗德黑兰大学附属医院的COVID-19幸存者在感染后6个月通过先前验证的问卷进行评估，该问卷基于Fukuda CFS/EM指南和DSM-5 PTSD检查表（DSM-5或PCL-5的创伤后应激障碍检查表），以确定是否存在应激障碍和慢性疲劳问题。共入组120例患者。疲劳症状检出率为17.5%。12例（10%）慢性特发性疲劳（CIF）筛查阳性，6例（5%）CFS样疲劳不足综合征（CFSWIFS）筛查阳性，3例（2.5%）CFS筛查阳性。PCL-5总分为9.27 ± 10.76（0-44分），PTSD患病率为5.8%。在调整CFS和PTSD、性别、合并症和磷酸氯喹给药后，没有显著相关性。获得的数据显示，CFS在COVID-19患者中的患病率与普通人群中的CFS患病率几乎相似。此外，COVID-19患者的PTSD与CFS风险增加无关。我们的研究表明，医疗机构应关注COVID-19爆发的心理后果。
As the SARS-COV-2 becomes a global pandemic, many researchers have a concern about the long COVID-19 complications. Chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME) is a persistent, debilitating, and unexplained fatigue disorder. We investigated psychological morbidities such as CFS and post-traumatic stress disorder (PTSD) among survivors of COVID-19 over 6 months. All COVID-19 survivors from the university-affiliated hospital of Tehran, Iran, were assessed 6 months after infection onset by a previously validated questionnaire based on the Fukuda guidelines for CFS/EM and DSM-5 Checklist for PTSD (The Post-traumatic Stress Disorder Checklist for DSM-5 or PCL-5) to determine the presence of stress disorder and chronic fatigue problems. A total of 120 patients were enrolled. The prevalence rate of fatigue symptoms was 17.5%. Twelve (10%) screened positive for chronic idiopathic fatigue (CIF), 6 (5%) for CFS-like with insufficient fatigue syndrome (CFSWIFS), and 3 (2.5%) for CFS. The mean total scores in PCL-5 were 9.27 ± 10.76 (range:0–44), and the prevalence rate of PTSD was 5.8%. There was no significant association after adjusting between CFS and PTSD, gender, comorbidities, and chloroquine phosphate administration. The obtained data revealed the prevalence of CFS among patients with COVID-19, which is almost similar to CFS prevalence in the general population. Moreover, PTSD in patients with COVID-19 is not associated with the increased risk of CFS. Our study suggested that medical institutions should pay attention to the psychological consequences of the COVID-19 outbreak.
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