Impossibility of Consistent Distance Estimation from Sequence Lengths Under the TKF91 Model

Impossibility of Consistent Distance Estimation from Sequence Lengths Under the TKF91 Model
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TKF91模型下不可能根据序列长度进行一致的距离估计

DOI:
10.1007/s11538-020-00801-3
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发表时间:
2020
影响因子:
3.5
通讯作者:
Roch, Sebastien
Roch, Sebastien
中科院分区:
数学4区
文献类型:
--
作者:
Fan, Wai-Tong Louis;Legried, Brandon;Roch, Sebastien

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我们考虑了系统发育中插入、缺失和替换序列进化的TKF91模型下的距离估计问题。在期望序列长度趋近于无穷大的渐近区域,我们证明了仅从序列长度不可能估计出一致的距离。更正式地,我们建立了不同距离上序列长度对的分布不能以趋近于1的概率来区分。
We consider the problem of distance estimation under the TKF91 model of sequence evolution by insertions, deletions and substitutions on a phylogeny. In an asymptotic regime where the expected sequence lengths tend to infinity, we show that no consistent distance estimation is possible from sequence lengths alone. More formally, we establish that the distributions of pairs of sequence lengths at different distances cannot be distinguished with probability going to one.
DOI: 10.1007/bf02193625
发表时间: 1991-08-01
影响因子: 3.9
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在密集分类单元采样下,TKF91 模型中祖先 DNA 序列的统计一致性和计算效率推断
DOI: 10.1007/s11538-020-00693-3
发表时间: 2020
影响因子: 3.5
作者:
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通讯作者: Roch, Sebastien
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发表时间: 2013-04-01
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序列进化的TKF模型的可逆性。
DOI: 10.1016/j.mbs.2005.12.025
发表时间: 2006
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DOI: 10.1007/bf00163848
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