The NC/Nga mouse: a model for atopic dermatitis.

The NC/Nga mouse: a model for atopic dermatitis.
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NC/Nga 小鼠:特应性皮炎模型。

DOI:
10.1016/s1357-4310(00)01683-x
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发表时间:
2000
期刊:
Molecular medicine today
影响因子:
--
通讯作者:
Konji Matsushima
Konji Matsushima
中科院分区:
--
文献类型:
--
作者:
Christian Vestergaard;Hiroyuki Yoneyama;Konji Matsushima

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图1所示。14周龄NC/Nga小鼠在非无菌条件下的大体病变(a)。病变在背部上部、耳朵和面部很明显。毛发已被去除以显示病变。(b)皮损皮肤活检的苏木精-伊红染色显示严重炎症、角化过度、棘层增生和角化不全。
Figure 1. The gross lesions of a 14-week-old NC/Nga mouse that has been kept under non-sterile conditions (a). The lesions are apparent on the upper part of the back on the ears and in the face. The hair has been removed to show the lesions.(b) A hematoxylin–eosin staining of a skin biopsy from lesional skin reveals heavy inflammation, hyperkeratosis, acanthosis and parakeratosis.
DOI: 10.1172/jci117408
发表时间: 1994-08-01
影响因子: 15.9
作者:
HAMID, Q;BOGUNIEWICZ, M;LEUNG, DYM
通讯作者: LEUNG, DYM