Trends in mortality from alcohol, opioid, and combined alcohol and opioid poisonings by sex, educational attainment, and race and ethnicity for the United States 2000-2019.
Trends in mortality from alcohol, opioid, and combined alcohol and opioid poisonings by sex, educational attainment, and race and ethnicity for the United States 2000-2019.
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饮酒，阿片类药物以及通过性别，教育程度以及2000 - 2019年美国种族和种族的酒精和阿片类药物中毒的死亡率趋势。
DOI：
10.1186/s12916-022-02590-z
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发表时间：
2022-10-24
期刊：
影响因子：
9.3
通讯作者：
Probst, Charlotte
中科院分区：
文献类型：
--
作者：
Buckley, Charlotte;Ye, Yu;Kerr, William C.;Mulia, Nina;Puka, Klajdi;Rehm, Jurgen;Probst, Charlotte
关键词：
持续的阿片类药物流行病和酒精相关死亡率的增加是美国的主要公共卫生问题，有充分证据表明，受教育程度低和受教育程度高的群体受到影响的程度不平等。这项研究旨在量化美国教育和种族和民族群体之间在阿片类药物，酒精以及酒精和阿片类药物联合中毒的性别特异性死亡率方面随时间的差异。国家生命统计系统（NVSS）的2000-2019年多死因文件与2000-2019年当前人口调查的人口计数一起使用。使用ICD-10编码分配酒精、阿片类药物以及酒精和阿片类药物联合中毒。按性别分层的广义最小二乘回归模型量化了教育与种族和族裔群体之间的差异以及教育不平等随时间的变化。2000年至2019年，阿片类药物中毒死亡人数增加了6.4倍，酒精和阿片类药物中毒死亡人数增加了4.6倍，酒精中毒死亡人数增加了2.1倍。所有中毒结果均观察到教育不平等，随着时间的推移，仅阿片类药物死亡率以及酒精和阿片类药物死亡率的增加。对于非西班牙裔白色美国人来说，阿片类药物中毒的教育不平等最大，低教育群体的比例是高教育群体的7.5倍（男性）和7.2倍（女性）。酒精和阿片类药物联合中毒对非西班牙裔黑人男性和女性（相对于非西班牙裔白色人）的教育不平等更大，低教育群体的比率是高教育群体的8.9倍（男性）和10.9倍（女性）。对于所有类型的中毒，我们的分析表明，低学历和高学历人群之间的差距越来越大，非西班牙裔黑人和白色男性和女性阿片类药物中毒的不平等程度最大。这项研究强调了人口亚组，例如受教育程度低的个人，他们可能处于酒精和阿片类药物联合中毒死亡率增加的最高风险。因此，这些发现对于制定有针对性的公共卫生干预措施以降低中毒死亡率和与之相关的社会经济不平等至关重要。在线版本包含补充材料，可通过10.1186/s12916-022-02590-z获得。
The ongoing opioid epidemic and increases in alcohol-related mortality are key public health concerns in the USA, with well-documented inequalities in the degree to which groups with low and high education are affected. This study aimed to quantify disparities over time between educational and racial and ethnic groups in sex-specific mortality rates for opioid, alcohol, and combined alcohol and opioid poisonings in the USA. The 2000–2019 Multiple Cause of Death Files from the National Vital Statistics System (NVSS) were used alongside population counts from the Current Population Survey 2000–2019. Alcohol, opioid, and combined alcohol and opioid poisonings were assigned using ICD-10 codes. Sex-stratified generalized least square regression models quantified differences between educational and racial and ethnic groups and changes in educational inequalities over time. Between 2000 and 2019, there was a 6.4-fold increase in opioid poisoning deaths, a 4.6-fold increase in combined alcohol and opioid poisoning deaths, and a 2.1-fold increase in alcohol poisoning deaths. Educational inequalities were observed for all poisoning outcomes, increasing over time for opioid-only and combined alcohol and opioid mortality. For non-Hispanic White Americans, the largest educational inequalities were observed for opioid poisonings and rates were 7.5 (men) and 7.2 (women) times higher in low compared to high education groups. Combined alcohol and opioid poisonings had larger educational inequalities for non-Hispanic Black men and women (relative to non-Hispanic White), with rates 8.9 (men) and 10.9 (women) times higher in low compared to high education groups. For all types of poisoning, our analysis indicates wide and increasing gaps between those with low and high education with the largest inequalities observed for opioid-involved poisonings for non-Hispanic Black and White men and women. This study highlights population sub-groups such as individuals with low education who may be at the highest risk of increasing mortality from combined alcohol and opioid poisonings. Thereby the findings are crucial for the development of targeted public health interventions to reduce poisoning mortality and the socioeconomic inequalities related to it. The online version contains supplementary material available at 10.1186/s12916-022-02590-z.
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影响因子：
4.2
作者：
Gomes, Tara;Juurlink, David N.;van den Brink, Wim
通讯作者：
van den Brink, Wim
影响因子：
3.4
作者：
Karriker-Jaffe, Katherine J.;Zemore, Sarah E.
通讯作者：
Zemore, Sarah E.
DOI：
10.1073/pnas.2024777118
发表时间：
2021-03-16
影响因子：
11.1
作者：
Case A;Deaton A
通讯作者：
Deaton A
DOI：
10.1136/injuryprev-2020-043951
发表时间：
2021-10
期刊：
Injury prevention : journal of the International Society for Child and Adolescent Injury Prevention
影响因子：
--
作者：
Kerr WC;Ye Y;Williams E;Mulia N;Cherpitel CJ
通讯作者：
Cherpitel CJ
影响因子：
3.3
作者：
Saloner, Brendan;McGinty, Emma E.;Sherman, Susan G.
通讯作者：
Sherman, Susan G.