The small subunit processome in ribosome biogenesis—progress and prospects.

The small subunit processome in ribosome biogenesis—progress and prospects.
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核糖体生物发生中的小亚基过程 - 前景和前景。

DOI:
10.1002/wrna.57
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发表时间:
2011-01
影响因子:
7.3
通讯作者:
Baserga, Susan J.
Baserga, Susan J.
中科院分区:
生物学2区
文献类型:
--
作者:
Phipps, Kathleen R.;Charette, J. Michael;Baserga, Susan J.

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小亚基(SSU)过程组是一个2.2MDA核糖核蛋白复合体,参与真核核糖体SSU的加工、组装和成熟。在过去的40年里,SSU生物发生中涉及的许多因素的身份已经被阐明。然而,随着我们理解的增加,关于这一复杂过程的性质的问题也在增加。对组件进行分类是了解系统分子工作原理的第一步。这篇综述将集中在识别核糖体生物发生的成分如何导致了解这些因素,蛋白质和RNA一样,是如何相互作用形成亚复合体的,重点是小的核糖体亚单位。我们还将探索亚复合体组装的知识如何帮助我们理解核糖体合成系统的整体工作原理。
The small subunit (SSU) processome is a 2.2 MDa ribonucleoprotein complex involved in the processing, assembly and maturation of the SSU of eukaryotic ribosomes. The identities of many of the factors involved in SSU biogenesis have been elucidated over the past 40 years. However, as our understanding increases, so do the number of questions about the nature of this complicated process. Cataloguing the components is the first step towards understanding the molecular workings of a system. This review will focus on how identifying components of ribosome biogenesis has led to the knowledge of how these factors, protein and RNA alike, associate with one another into sub-complexes, with a concentration on the small ribosomal subunit. We will also explore how this knowledge of sub-complex assembly has informed our understanding of the workings of the ribosome synthesis system as a whole.
DOI: 10.1186/1471-2164-10-528
发表时间: 2009-11-16
期刊: BMC genomics
影响因子: 4.4
作者:
Charette JM;Gray MW
通讯作者: Gray MW
DOI: 10.1126/science.1176099
发表时间: 2009-09-11
期刊: Science (New York, N.Y.)
影响因子: --
作者:
Bleichert F;Gagnon KT;Brown BA 2nd;Maxwell ES;Leschziner AE;Unger VM;Baserga SJ
通讯作者: Baserga SJ
DOI: 10.1093/nar/gki815
发表时间: 2005
影响因子: 14.9
作者:
Borovjagin AV;Gerbi SA
通讯作者: Gerbi SA
DOI: 10.1091/mbc.e04-06-0515
发表时间: 2004-11-01
影响因子: 3.3
作者:
Bernstein, KA;Baserga, SJ
通讯作者: Baserga, SJ
DOI: 10.1091/mbc.e06-06-0512
发表时间: 2007-03-01
影响因子: 3.3
作者:
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通讯作者: Baserga, Susan J.