A plant lipocalin promotes retinal-mediated oscillatory lateral root initiation.
A plant lipocalin promotes retinal-mediated oscillatory lateral root initiation.
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植物脂质运载蛋白促进视网膜介导的振荡侧根发生。
DOI:
10.1126/science.abf7461
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发表时间:
2021-09-24
期刊:
影响因子:
--
通讯作者:
Benfey PN
中科院分区:
文献类型:
--
作者:
Dickinson AJ;Zhang J;Luciano M;Wachsman G;Sandoval E;Schnermann M;Dinneny JR;Benfey PN
In Arabidopsis, de novo organogenesis of lateral roots is patterned by an oscillatory mechanism called the root clock, which is dependent on unidentified metabolites. To determine if retinoids regulate the root clock, we used a chemical reporter for retinaldehyde (retinal) binding proteins. We found that retinal binding precedes the root clock and predicts sites of lateral root organogenesis. Application of retinal increased root clock oscillations and promoted lateral root formation. Expression of an Arabidopsis protein with homology to vertebrate retinoid binding proteins, TEMPERATURE INDUCED LIPOCALIN (TIL) oscillates in the region of retinal binding to the reporter, confers retinal binding activity in a heterologous system, and when mutated, decreases retinal sensitivity. These results demonstrate a role for retinal and its binding partner in lateral root organogenesis.
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