Alcohol, Tobacco, and Comorbid Psychiatric Disorders and Associations With Sexual Identity and Stress-Related Correlates.
Alcohol, Tobacco, and Comorbid Psychiatric Disorders and Associations With Sexual Identity and Stress-Related Correlates.
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DOI：
10.1176/appi.ajp.2020.20010005
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发表时间：
2020-11-01
期刊：
影响因子：
--
通讯作者：
McCabe SE
中科院分区：
文献类型：
--
作者：
Evans-Polce RJ;Kcomt L;Veliz PT;Boyd CJ;McCabe SE
研究美国异性恋者、双性恋者和男/女同性恋者中与酒精使用障碍(AUD)和烟草使用障碍(TUD)相关的精神共病，以及与压力相关的因素是否可以预测共病。我们使用国家酒精和相关条件流行病学研究-III(2012-2013，n=36,309)的数据来检查过去一年的AUD或过去一年的TUD与过去一年的共存：(1)焦虑症，(2)情绪障碍，(3)按性别(异性恋、双性恋、男/女同性恋者)和性别划分的创伤后应激障碍(PTSD)。我们还研究了压力相关因素和社会支持与合并症的关系。合并症在妇女和性少数群体中更为普遍，尤其是双性恋妇女。在符合过去一年AUD标准的双性恋者(55%)和男/女同性恋者(51%)中，超过一半的人患有精神疾病，而符合过去一年AUD标准的异性恋者中只有三分之一患有精神疾病。在符合过去一年TUD标准的患者中，也发现了类似的差异。在性少数群体中，性取向歧视的频率(显著AOR范围=1.08-1.10)、应激性生活事件的数量(显著AOR范围=1.25-1.43)和ACE(显著AOR范围=1.04-1.18)与合并疾病的几率较高。较大的社会支持与TUD合并症呈负相关(显著的AOR范围=0.96-0.97)。这项研究表明，需要综合使用药物和心理健康预防和治疗计划，特别是对于那些认为自己是性少数的人。性少数群体经历的压力增加可能是导致这些高水平共病的重要驱动因素。
To examine psychiatric comorbidities associated with alcohol use disorders (AUDs) and with tobacco use disorders (TUDs) among heterosexual, bisexual, and gay/lesbian men and women in the U.S. and whether stress-related factors were predictive of comorbidities. We used data from the National Epidemiologic Study on Alcohol and Related Conditions-III (2012–2013, n=36,309) to examine the co-occurrence of past-year AUD or past-year TUD with past-year: (1) anxiety disorders, (2) mood disorders, and (3) post-traumatic stress disorder (PTSD) by sexual identity (heterosexual, bisexual, gay/lesbian) and sex. We also examined the association of stress-related factors and social support with presence of comorbidities. Comorbidities were more prevalent among women and sexual minorities, particularly bisexual women. More than half of bisexual (55%) and gay/lesbian (51%) individuals who met criteria for a past-year AUD had a psychiatric comorbidity, while only one-third of heterosexual individuals who met criteria for a past-year AUD did. Similardifferences were found among those who met criteria for a past-year TUD. Among sexual minorities, frequency of sexual orientation discrimination (significant aOR range=1.08–1.10), number of stressful life events (significant aOR range=1.25–1.43), and ACEs (significant aOR range=1.04–1.18) were associated with greater odds of comorbidities. Greater social support was inversely associated with TUD comorbidities (significant aOR range=0.96–0.97). This research suggests integrated substance use and mental health prevention and treatment programs are needed particularly for individuals who identify as sexual minorities. The increased stressors experienced by sexual minority individuals may be important drivers of these high levels of comorbidities.
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影响因子：
12.7
作者：
McCabe, Sean Esteban;Bostwick, Wendy B.;Boyd, Carol J.
通讯作者：
Boyd, Carol J.
影响因子：
6
作者：
Kahle, Erin M.;Veliz, Phil;Boyd, Carol J.
通讯作者：
Boyd, Carol J.
影响因子：
12.7
作者：
Hatzenbuehler, Mark L.;McLaughlin, Katie A.;Hasin, Deborah S.
通讯作者：
Hasin, Deborah S.
影响因子：
4.4
作者：
Merikangas, KR;Mehta, RL;Kessler, RC
通讯作者：
Kessler, RC
影响因子：
3.3
作者：
Bostwick, Wendy B.;Boyd, Carol J.;McCabe, Sean Esteban
通讯作者：
McCabe, Sean Esteban