Psychological and Cognitive Functioning Among Patients Receiving Outpatient Rehabilitation for Post-COVID Sequelae: An Observational Study.

Psychological and Cognitive Functioning Among Patients Receiving Outpatient Rehabilitation for Post-COVID Sequelae: An Observational Study.
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DOI:
10.1016/j.apmr.2022.09.013
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发表时间:
2023-01
影响因子:
4.3
通讯作者:
Pezzin, Liliana E.
Pezzin, Liliana E.
中科院分区:
医学1区
文献类型:
--
作者:
Abramoff, Benjamin A.;Dillingham, Timothy R.;Brown, Lily A.;Caldera, Franklin;Caldwell, Katherine M.;McLarney, Mitra;McGinley, Emily L.;Pezzin, Liliana E.

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描述因 SARS-CoV-2 感染急性后遗症 (PASC) 接受门诊康复治疗的个体的特征。此外,检查与心理和认知功能以及健康相关生活质量变化相关的因素。观察性研究。美国大型三级城市卫生系统的新冠肺炎 (COVID-19) 康复门诊。患有持续性后遗症的 COVID-19 幸存者 (N=324)。 : 不适用。使用多变量逻辑回归和线性回归模型来检查与新冠肺炎幸存者的严重焦虑、严重抑郁、创伤后应激障碍(PTSD)、认知障碍和自我报告的健康相关生活质量相关的因素。在因持续的新冠症状寻求治疗的幸存者中,约 38% 患有严重焦虑症,31.8% 患有严重抑郁症,43% 患有中度至重度 PTSD 症状,17.5% 患有认知障碍。他们的健康相关生活质量大大低于普通人群(-26%)和患有其他慢性病的人。即使在控制了年龄、性别、急性感染的初始严重程度以及诊断后的时间后,穷人和非裔美国人/黑人在感染新冠病毒后也会经历更严重的心理和认知后遗症。有证据表明,患者的种族和社会经济地位的结果存在持续差异,即使是那些能够获得急性新冠肺炎康复护理的患者,也令人担忧,并对 PASC 政策和计划的制定产生重大影响。
To describe the characteristics of individuals receiving outpatient rehabilitation for post-acute sequelae of SARS-CoV-2 infection (PASC). Further, to examine factors associated with variation in their psychological and cognitive functioning and health-related quality of life. Observational study. Outpatient COVID-19 recovery clinic at a large, tertiary, urban health system in the US. COVID-19 survivors with persistent sequelae (N=324). : Not applicable. Multivariable logistic and linear regression models were used to examine factors associated with COVID survivors’ experience of severe anxiety, severe depression, post-traumatic stress disorder (PTSD), cognitive impairment, and self-reported health-related quality of life. About 38% of survivors seeking care for their persistent COVID symptoms suffered from severe anxiety, 31.8% from severe depression, 43% experiencing moderate to severe PTSD symptomology, and 17.5% had cognitive impairment. Their health-related quality of life was substantially lower than that of the general population (-26%) and of persons with other chronic conditions. Poor and African American/Black individuals experienced worse psychological and cognitive sequelae after COVID19 infection, even after controlling for age, sex, initial severity of the acute infection, and time since diagnosis. Evidence of consistent disparities in outcomes by the patients’ race and socioeconomic status, even among those with access to post-acute COVID rehabilitation care, are concerning and have significant implications for PASC policy and program development.
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