Practicable assessment of cochlear size and shape from clinical CT images.

Practicable assessment of cochlear size and shape from clinical CT images.
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DOI:
10.1038/s41598-021-83059-6
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发表时间:
2021-02-10
期刊:
影响因子:
4.6
通讯作者:
Bance ML
Bance ML
中科院分区:
综合性期刊3区
文献类型:
--
作者:
Gee AH;Zhao Y;Treece GM;Bance ML

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人类耳蜗的大小和形状存在相当大的个体差异,对人工耳蜗植入有明显的影响。根据术前计算机断层扫描(CT)图像表征特定耳蜗的能力将允许临床医生个性化选择电极、手术方法和术后程控。在这项研究中,我们提出了一种快速,实用和免费提供的方法来估计耳蜗的大小和形状从临床CT。所采取的方法是使用统计形状模型或局部仿射变形(LAD)将模板表面拟合到CT数据。拟合后,我们测量耳蜗的大小,管道长度和一种新的措施,基底转向非平面性,我们认为这可能与插入创伤的风险。将来自18个微型CT扫描的便利样本的金标准测量值与从相同微型CT扫描合成的低分辨率、噪声、伪临床数据估计的相同量进行比较。使用LAD方法获得了最佳结果,对于非平面性、耳蜗大小和导管长度,预期误差为金标准样本范围的8-17%。
There is considerable interpersonal variation in the size and shape of the human cochlea, with evident consequences for cochlear implantation. The ability to characterize a specific cochlea, from preoperative computed tomography (CT) images, would allow the clinician to personalize the choice of electrode, surgical approach and postoperative programming. In this study, we present a fast, practicable and freely available method for estimating cochlear size and shape from clinical CT. The approach taken is to fit a template surface to the CT data, using either a statistical shape model or a locally affine deformation (LAD). After fitting, we measure cochlear size, duct length and a novel measure of basal turn non-planarity, which we suggest might correlate with the risk of insertion trauma. Gold-standard measurements from a convenience sample of 18 micro-CT scans are compared with the same quantities estimated from low-resolution, noisy, pseudo-clinical data synthesized from the same micro-CT scans. The best results were obtained using the LAD method, with an expected error of 8–17% of the gold-standard sample range for non-planarity, cochlear size and duct length.
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影响因子: 6.1
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期刊: Ear and hearing
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