Recent advances and perspectives of postoperative neurological disorders in the elderly surgical patients.
Recent advances and perspectives of postoperative neurological disorders in the elderly surgical patients.
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老年外科患者术后神经系统疾病的最新进展和展望。
DOI：
10.1111/cns.13763
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发表时间：
2022-04
影响因子：
5.5
通讯作者：
Yu W
中科院分区：
文献类型：
--
作者：
Liu B;Huang D;Guo Y;Sun X;Chen C;Zhai X;Jin X;Zhu H;Li P;Yu W
术后神经系统疾病，包括术后谵妄（POD）、术后认知功能障碍（POCD）、术后隐匿性缺血性脑卒中及出血性脑卒中，是日益增多的老年手术人群面临的棘手临床问题。这些疾病会使术后功能恢复情况及长期生活质量恶化，给家庭和社会带来巨大的社会及经济负担。鉴于部分风险因素是可以改变的，了解易患因素和诱发因素，或许能推动针对每种疾病的个体化预防治疗。除预防之外，及时识别并治疗病因及症状，有助于术后神经系统疾病更好地康复，并降低长期认知障碍、残疾甚至死亡的风险。在此，我们总结这些术后并发症的诊断、风险因素、预防及治疗方法，重点介绍最新进展和展望。
本综述阐述了术后神经系统疾病的一般特征及最新循证知识，重点介绍了最新进展和展望。本综述梳理了有关术后神经系统疾病风险因素、预防及治疗的现有证据，以助力指导未来研究及临床管理。
Postoperative neurological disorders, including postoperative delirium (POD), postoperative cognitive dysfunction (POCD), postoperative covert ischemic stroke, and hemorrhagic stroke, are challenging clinical problems in the emerging aged surgical population. These disorders can deteriorate functional outcomes and long‐term quality of life after surgery, resulting in a substantial social and financial burden to the family and society. Understanding predisposing and precipitating factors may promote individualized preventive treatment for each disorder, as several risk factors are modifiable. Besides prevention, timely identification and treatment of etiologies and symptoms can contribute to better recovery from postoperative neurological disorders and lower risk of long‐term cognitive impairment, disability, and even death. Herein, we summarize the diagnosis, risk factors, prevention, and treatment of these postoperative complications, with emphasis on recent advances and perspectives. This review described general features and the latest evidence‐based knowledge of postoperative neurological disorders with emphasis on recent advances and perspectives. This review mapped the existing evidence regarding risk factors, prevention, and treatment for postoperative neurological disorders to help guide future research and clinical management.
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影响因子：
2.9
作者：
Chen F;Duan G;Wu Z;Zuo Z;Li H
通讯作者：
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影响因子：
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作者：
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通讯作者：
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DOI：
10.1055/a-0853-3060
发表时间：
2019-11-01
影响因子：
0.4
作者：
Borchers, Friedrich;Knaak, Cornelia;Spies, Claudia
通讯作者：
Spies, Claudia