Advanced materials and processing for drug delivery: the past and the future.

Advanced materials and processing for drug delivery: the past and the future.
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药物输送的高级材料和处理:过去和未来。

DOI:
10.1016/j.addr.2012.10.003
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发表时间:
2013-01
影响因子:
16.1
通讯作者:
Leong, Kam W.
Leong, Kam W.
中科院分区:
医学1区
文献类型:
--
作者:
Zhang, Ying;Chan, Hon Fai;Leong, Kam W.

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设计和合成高效的药物递送系统对医药和医疗保健至关重要。材料创新和纳米技术协同推动了药物传递的进步。材料化学的创新使可生物降解、生物兼容、环境响应和有针对性的传递系统的产生成为可能。纳米技术能够控制颗粒药物输送系统的大小、形状和多功能。在这篇综述中,我们重点介绍了药物传递系统的材料创新和加工,以及这些进展如何塑造了过去,并可能影响药物传递的未来。
Design and synthesis of efficient drug delivery systems are of vital importance for medicine and healthcare. Materials innovation and nanotechnology have synergistically fueled the advancement of drug delivery. Innovation in material chemistry allows the generation of biodegradable, biocompatible, environment-responsive, and targeted delivery systems. Nanotechnology enables control over size, shape and multi-functionality of particulate drug delivery systems. In this review, we focus on the materials innovation and processing of drug delivery systems and how these advances have shaped the past and may influence the future of drug delivery.
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