Central regulation of energy metabolism by estrogens.
Central regulation of energy metabolism by estrogens.
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DOI：
10.1016/j.molmet.2018.05.012
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发表时间：
2018-09
影响因子：
8.1
通讯作者：
López M
中科院分区：
文献类型：
--
作者：
Xu Y;López M
Estrogenic actions in the brain prevent obesity. Better understanding of the underlying mechanisms may facilitate development of new obesity therapies. This review focuses on the critical brain regions that mediate effects of estrogens on food intake and/or energy expenditure, the molecular signals that are involved, and the functional interactions between brain estrogens and other signals modulating metabolism. Body weight regulation by estrogens in male brains will also be discussed. 17β-estradiol acts in the brain to regulate energy homeostasis in both sexes. It can inhibit feeding and stimulate brown adipose tissue thermogenesis. A better understanding of the central actions of 17β-estradiol on energy balance would provide new insight for the development of therapies against obesity in both sexes.
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影响因子：
4.4
作者：
Contreras C;Gonzalez F;Fernø J;Diéguez C;Rahmouni K;Nogueiras R;López M
通讯作者：
López M
影响因子：
4.8
作者：
Callewaert, Filip;Venken, Katrien;Vanderschueren, Dirk
通讯作者：
Vanderschueren, Dirk
影响因子：
4.8
作者：
Amateau, SK;Alt, JJ;McCarthy, MM
通讯作者：
McCarthy, MM
影响因子：
8.1
作者：
Alvarez-Crespo M;Csikasz RI;Martínez-Sánchez N;Diéguez C;Cannon B;Nedergaard J;López M
通讯作者：
López M
影响因子：
15.9
作者：
Cao, Xuehong;Xu, Pingwen;Xu, Yong
通讯作者：
Xu, Yong