Objective Endoscopic Analysis with Linked Color Imaging regarding Gastric Mucosal Atrophy: A Pilot Study.

Objective Endoscopic Analysis with Linked Color Imaging regarding Gastric Mucosal Atrophy: A Pilot Study.
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DOI:
10.1155/2017/5054237
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发表时间:
2017
影响因子:
2
通讯作者:
Murakami K
Murakami K
中科院分区:
医学4区
文献类型:
--
作者:
Mizukami K;Ogawa R;Okamoto K;Shuto M;Fukuda K;Sonoda A;Matsunari O;Hirashita Y;Okimoto T;Kodama M;Murakami K

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我们的目的是确定链接彩色成像(LCI),一种新的图像增强内窥镜,增强粘膜颜色的细微差异,是否可以区分内镜下粘膜萎缩的边界。本研究纳入30例萎缩性胃炎患者。在内窥镜中,我们使用LCI和白光成像(WLI)连续拍摄相同构图的图像。在每张图像中,萎缩和非萎缩粘膜的颜色值使用1976年国际照明委员会(L∗,a∗,b∗)颜色空间进行量化。萎缩边界的颜色差异,定义为萎缩和非萎缩粘膜之间颜色值的欧几里得距离,在整个队列中比较WLI和LCI之间的颜色差异,并分别对幽门螺杆菌感染状态的患者进行比较。我们发现,在30例患者的90分总样本中,LCI的色差明显高于WLI。LCI为14.79±6.68,WLI为11.06±5.44 (P < 0.00001)。LCI在幽门螺杆菌感染组(P = 0.00003)和幽门螺杆菌根除组(P = 0.00002)也更有效。在胃炎的各种情况下,无论幽门螺杆菌感染状态如何,LCI都可以在内镜下清晰地显示萎缩边界。
We aimed to determine whether linked color imaging (LCI), a new image-enhanced endoscopy that enhances subtle differences in mucosal colors, can distinguish the border of endoscopic mucosal atrophy. This study included 30 patients with atrophic gastritis. In endoscopy, we continuously took images in the same composition with both LCI and white light imaging (WLI). In each image, the color values of atrophic and nonatrophic mucosae were quantified using the International Commission on Illumination 1976 (L∗, a∗, b∗) color space. Color differences at the atrophic border, defined as Euclidean distances of color values between the atrophic and nonatrophic mucosae, were compared between WLI and LCI for the overall cohort and separately for patients with Helicobacter pylori infection status. We found that the color difference became significantly higher with LCI than with WLI in the overall samples of 90 points in 30 patients. LCI was 14.79 ± 6.68, and WLI was 11.06 ± 5.44 (P < 0.00001). LCI was also more effective in both of the Helicobacter pylori-infected group (P = 0.00003) and the Helicobacter pylori-eradicated group (P = 0.00002). LCI allows clear endoscopic visualization of the atrophic border under various conditions of gastritis, regardless of Helicobacter pylori infection status.
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