NR4A1 destabilizes TNF mRNA in microglia and modulates stroke outcomes.
NR4A1 destabilizes TNF mRNA in microglia and modulates stroke outcomes.
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DOI:
10.1371/journal.pbio.3002226
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发表时间:
2023-07
期刊:
影响因子:
9.8
通讯作者:
Yao, Yao
中科院分区:
文献类型:
--
作者:
Yao, Yao
Microglia play a dual role in stroke depending on their pro-inflammatory and anti-inflammatory polarization. A study in PLOS Biology identifies a new mechanism, through which the transcription factor NR4A1 negatively regulates TNF expression in microglia. Microglia play a dual role in stroke depending on their pro-inflammatory and anti-inflammatory polarization. This Primer explores a PLOS Biology study that identifies a new mechanism through which the transcription factor NR4A1 negatively regulates TNF expression in microglia.
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影响因子:
9.8
作者:
Liu, Pinyi;Chen, Yan;Zhang, Zhi;Yuan, Zengqiang;Sun, Jian-Guang;Xia, Shengnan;Cao, Xiang;Chen, Jian;Zhang, Cun-Jin;Chen, Yanting;Zhan, Hui;Jin, Yuexinzi;Bao, Xinyu;Gu, Yue;Zhang, Meijuan;Xu, Yun
通讯作者:
Xu, Yun
影响因子:
15.9
作者:
Kreutzberg, GW
通讯作者:
Kreutzberg, GW
影响因子:
20.1
作者:
Hamers, Anouk A. J.;Vos, Mariska;de Vries, Carlie J. M.
通讯作者:
de Vries, Carlie J. M.
DOI:
10.4049/jimmunol.1600638
发表时间:
2017-05-15
期刊:
Journal of immunology (Baltimore, Md. : 1950)
影响因子:
--
作者:
Rothe T;Ipseiz N;Faas M;Lang S;Perez-Branguli F;Metzger D;Ichinose H;Winner B;Schett G;Krönke G
通讯作者:
Krönke G
影响因子:
25
作者:
Mancuso, Renzo;Van den Daele, Johanna;De Strooper, Bart
通讯作者:
De Strooper, Bart