Acute flaccid myelitis: A clinical review of US cases 2012-2015.

Acute flaccid myelitis: A clinical review of US cases 2012-2015.
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DOI:
10.1002/ana.24730
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发表时间:
2016-09
影响因子:
11.2
通讯作者:
Dominguez, Samuel R.
Dominguez, Samuel R.
中科院分区:
医学1区
文献类型:
--
作者:
Messacar, Kevin;Schreiner, Teri L.;Van Haren, Keith;Yang, Michele;Glaser, Carol A.;Tyler, Kenneth L.;Dominguez, Samuel R.

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该综述强调了2012年至2015年美国与前肌麻痹相关的急性弛缓性麻痹病例增加的临床特征。急性弛缓性脊髓炎是指急性弛缓性肢体无力,影像学检查显示脊髓灰质病变,或电诊断测试显示脊髓运动神经元损伤的证据。虽然有些人表现出改善运动无力和功能缺陷,大多数有残留的弱点一年或更长时间后发病。流行病学证据和生物相容性支持肠道病毒D68与美国最近急性弛缓性肌炎病例增加之间的关联。
This review highlights clinical features of the increasing cases of acute flaccid paralysis associated with anterior myelitis noted in the United States from 2012 to 2015. Acute flaccid myelitis refers to acute flaccid limb weakness with spinal cord gray matter lesions on imaging or evidence of spinal cord motor neuron injury on electrodiagnostic testing. Although some individuals demonstrated improvement in motor weakness and functional deficits, most have residual weakness a year or more after onset. Epidemiological evidence and biological plausibility support an association between enterovirus D68 and the recent increase in acute flaccid myelitis cases in the United States.
急性弛缓性脊髓炎儿童肠道病毒 D68 感染,美国科罗拉多州,2014 年。
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