Patterns of change in cardiovascular risk assessments and ankle brachial index among Puerto Rican adults.
Patterns of change in cardiovascular risk assessments and ankle brachial index among Puerto Rican adults.
复制标题
DOI：
10.1371/journal.pone.0245236
复制
发表时间：
2021
期刊：
影响因子：
3.7
通讯作者：
Tucker KL
中科院分区：
文献类型：
--
作者：
Noel SE;Cornell DJ;Zhang X;Mirochnick JC;Mattei J;Falcón LM;Tucker KL
与墨西哥裔美国人相比，波多黎各成年人患外周动脉疾病（PAD）的几率更高。有限的研究已经检查了临床风险评估评分和ABI指标之间的关系，在这一人群中。使用来自波士顿波多黎各健康研究（BPRHS）（n = 370-583）的2004-2015年数据，在波多黎各成人（45-75岁）中评估了5年随访时的横截面、5年变化以及肩关节风险评分（FRS）和非稳态负荷（AL）与踝臂指数（ABI）的变化模式。在基线、2年和5年随访时计算FRS和AL。多变量线性回归模型用于检查FRS和AL的横截面和5年变化以及5年ABI。潜在生长混合模型确定了FRS和AL在5年内的轨迹，多变量线性回归模型用于检验5年内轨迹组之间的相关性。5年时FRS较大和FRS较基线增加与5年时ABI较低相关（分别为β =-0.149，P = 0.010; β =-0.171，P = 0.038）。在横断面或变化分析中，AL与ABI无关。FRS轨迹低上升（与无变化相比）和AL轨迹中度上升（与低上升相比）的受试者的5年ABI较低（分别为β =-0.025，P = 0.044; β =-0.016，P = 0.023）。FRS是一个更好的ABI的整体预测，与AL。波多黎各成年人，一个研究不足的人口与较高的FRS超过5年，可能会受益于密集的危险因素修改，以减少PAD的风险。需要进一步研究FRS和AL与PAD发展之间的关系。
Puerto Rican adults have higher odds of peripheral artery disease (PAD) compared with Mexican Americans. Limited studies have examined relationships between clinical risk assessment scores and ABI measures in this population. Using 2004–2015 data from the Boston Puerto Rican Health Study (BPRHS) (n = 370–583), cross-sectional, 5-y change, and patterns of change in Framingham Risk Score (FRS) and allostatic load (AL) with ankle brachial index (ABI) at 5-y follow-up were assessed among Puerto Rican adults (45–75 y). FRS and AL were calculated at baseline, 2-y and 5-y follow-up. Multivariable linear regression models were used to examine cross-sectional and 5-y changes in FRS and AL with ABI at 5-y. Latent growth mixture modeling identified trajectories of FRS and AL over 5-y, and multivariable linear regression models were used to test associations between trajectory groups at 5-y. Greater FRS at 5-y and increases in FRS from baseline were associated with lower ABI at 5-y (β = -0.149, P = 0.010; β = -0.171, P = 0.038, respectively). AL was not associated with ABI in cross-sectional or change analyses. Participants in low-ascending (vs. no change) FRS trajectory, and participants in moderate-ascending (vs. low-ascending) AL trajectory, had lower 5-y ABI (β = -0.025, P = 0.044; β = -0.016, P = 0.023, respectively). FRS was a better overall predictor of ABI, compared with AL. Puerto Rican adults, an understudied population with higher FRS over 5 years, may benefit from intensive risk factor modification to reduce risk of PAD. Additional research examining relationships between FRS and AL and development of PAD is warranted.
登录
查看更多内容
影响因子：
120.7
作者：
Fowkes, F. G. R.;Murray, G. D.;Butcher, I.;Heald, C. L.;Lee, R. J.;Chambless, L. E.;Folsom, A. R.;Hirsch, A. T.;Dramaix, M.;deBacker, G.;Wautrecht, J-C.;Kornitzer, M.;Newman, A. B.;Cushman, M.;Sutton-Tyrrell, K.;Lee, A. J.;Price, J. F.;d'Agostino, R. B.;Murabito, J. M.;Norman, P. E.;Jamrozik, K.;Curb, J. D.;Masaki, K. H.;Rodriquez, B. L.;Dekker, J. M.;Bouter, L. M.;Heine, R. J.;Nijpels, G.;Stehouwer, C. D. A.;Ferrucci, L.;McDermott, M. M.;Stoffers, H. E.;Hooi, J. D.;Knottnerus, J. A.;Ogren, M.;Hedblad, B.;Witteman, J. C.;Breteler, M. M. B.;Hunink, M. G. M.;Hofman, A.;Criqui, M. H.;Langer, R. D.;Fronek, A.;Hiatt, W. R.;Hamman, R.;Resnick, H. E.;Guralnik, J.;McDermott, M. M.
通讯作者：
McDermott, M. M.
影响因子：
7.1
作者：
Bermudez, OI;Velez-Carrasco, W;Tucker, KL
通讯作者：
Tucker, KL
影响因子：
158.5
作者：
CRIQUI, MH;LANGER, RD;BROWNER, D
通讯作者：
BROWNER, D
影响因子：
120.7
作者：
Bhatt, DL;Steg, PG;Zuzarte, K
通讯作者：
Zuzarte, K
DOI：
10.1590/s1020-49892012000800007
发表时间：
2012-08-01
期刊：
Revista Panamericana de Salud Pública
影响因子：
--
作者：
Cortes-Bergoderi, Mery;Thomas, Randal J.;Lopez-Jimenez, Francisco
通讯作者：
Lopez-Jimenez, Francisco