Preferences for pre-exposure prophylaxis for HIV: A systematic review of discrete choice experiments.
Preferences for pre-exposure prophylaxis for HIV: A systematic review of discrete choice experiments.
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DOI：
10.1016/j.eclinm.2022.101507
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发表时间：
2022-09
影响因子：
15.1
通讯作者：
中科院分区：
文献类型：
--
作者：
我们的目的是系统地回顾健康偏好文献，使用离散选择实验（DCE），基于属性的陈述偏好方法，调查患者对HIV暴露前预防（PrEP）的偏好。于2021年7月1日在PubMed、Scopus、CINAHL和Embase中进行了检索，并于2021年11月3日更新。我们使用两个概念来创建我们的搜索策略：（1）离散选择实验/联合分析/最佳-最差缩放，以及（2）HIV PrEP。该研究已在PROSPERO（CRD 42021267026）中注册。总共识别了1060项研究，其中18项纳入分析。检查了各种属性，包括给药方案，PrEP产品的类型，副作用，其他副作用，成本，有效性，分发地点和额外的支持服务。给药频率、成本、PrEP的有效性、分发地点和副作用是VCE中检查的最常见属性。尽管各亚群的偏好存在显著异质性，但总体而言，最重要的属性是成本（28%，5/18）、有效性（28%，5/18），其次是给药频率（17%，3/18）。值得注意的是，在所有这三个属性进行检查的研究中，一些人会用有效性来换取成本，反之亦然。确保PrEP是低成本或免费的，广泛传播其有效性的信息和减少给药频率的进步可以加速那些从PrEP中受益最多的人对PrEP的吸收。没有。
We aimed to systematically review the health preference literature using discrete choice experiments (DCEs), an attribute-based stated preference method, to investigate patient preferences for HIV pre-exposure prophylaxis (PrEP). A search in PubMed, Scopus, CINAHL, and Embase was conducted on July 1, 2021, and updated on November 3, 2021. We used two concepts to create our search strategy: (1) discrete choice experiments/conjoint analysis/best-worst scaling, and (2) HIV PrEP.The study is registered in PROSPERO (CRD42021267026). In total, 1060 studies were identified, and 18 were included in the analysis. Various attributes were examined, including dosing regimen, type of PrEP products, side effects, other side benefits, cost, effectiveness, dispensing venue, and additional support services. Dosing frequency, cost, the effectiveness of PrEP, dispensing venue, and side effects were the most common attributes examined in DCEs. Despite significant heterogeneity in preferences across subpopulations, overall, the most important attributes were cost (28%, 5/18), effectiveness (28%, 5/18) followed by dosing frequency (17%, 3/18). Notably, in studies where all of these three attributes were examined, some individuals would trade effectiveness for cost or vice versa. Ensuring PrEP is low cost or free, widely disseminating information of its effectiveness and advancements in reducing dosing frequency could accelerate the uptake of PrEP for those who would benefit from PrEP the most. None.
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DOI：
10.1097/qai.0000000000000993
发表时间：
2016-08-01
期刊：
Journal of acquired immune deficiency syndromes (1999)
影响因子：
--
作者：
Dimitrov DT;Mâsse BR;Donnell D
通讯作者：
Donnell D
影响因子：
50
作者：
Bavinton, Benjamin R.;Grulich, Andrew E.
通讯作者：
Grulich, Andrew E.
影响因子：
4.5
作者：
Bridges, John F. P.;Hauber, A. Brett;Mauskopf, Josephine
通讯作者：
Mauskopf, Josephine
影响因子：
3.8
作者：
Fonner, Virginia A.;Dalglish, Sarah L.;Grant, Robert M.
通讯作者：
Grant, Robert M.
影响因子：
4.4
作者：
Browne, Erica N.;Montgomery, Elizabeth T.;van der Straten, Ariane
通讯作者：
van der Straten, Ariane