The small cell variant of anaplastic large cell lymphoma.

The small cell variant of anaplastic large cell lymphoma.
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间变性大细胞淋巴瘤的小细胞变体。

DOI:
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发表时间:
2010
影响因子:
4.6
通讯作者:
J. Moncur
J. Moncur
中科院分区:
医学2区
文献类型:
--
作者:
T. Summers;J. Moncur

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间变性大细胞淋巴瘤是一组异质性造血系统肿瘤,其特征是 CD30 免疫阳性以及不同程度存在大的多形性“标志”细胞。原发性全身性间变性淋巴瘤激酶阳性间变性大细胞淋巴瘤是该组的一个子集。在间变性淋巴瘤激酶阳性的间变性大细胞淋巴瘤中描述了许多异质的组织形态学模式,并且所有模式都比间变性淋巴瘤激酶阴性病例具有更好的预后。我们对间变性大细胞淋巴瘤的小细胞变型进行了简短回顾,以促进这种难以识别的实体的诊断,该实体可能与反应性过程相混淆,通常表现为播散性疾病,并具有侵袭性的临床病程。
Anaplastic large cell lymphomas constitute a heterogeneous group of hematopoietic neoplasms that are characterized by immunopositivity for CD30 and the presence, in varying degrees, of large, pleomorphic "hallmark" cells. Primary systemic anaplastic lymphoma kinase-positive anaplastic large cell lymphomas are a subset of this group. Numerous heterogeneous histomorphologic patterns have been described in anaplastic lymphoma kinase-positive anaplastic large cell lymphomas, and all patterns tend to have a better prognosis than that found in anaplastic lymphoma kinase-negative cases. We provide a short review of the small cell variant of anaplastic large cell lymphoma to facilitate the diagnosis of this difficult-to-recognize entity, which may be confused with reactive processes, commonly presents with disseminated disease, and pursues an aggressive clinical course.
DOI: 10.1126/science.8122112
发表时间: 1994-03-04
期刊: SCIENCE
影响因子: 56.9
作者:
MORRIS, SW;KIRSTEIN, MN;LOOK, AT
通讯作者: LOOK, AT
DOI: 10.1182/blood.v91.6.2076
发表时间: 1998-03-15
期刊: BLOOD
影响因子: 20.3
作者:
Benharroch, D;Meguerian-Bedoyan, Z;Delsol, G
通讯作者: Delsol, G