Effects of Indwelling Pleural Catheter on Severe Acute Pancreatitis: A Retrospective Study.
Effects of Indwelling Pleural Catheter on Severe Acute Pancreatitis: A Retrospective Study.
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DOI：
10.1155/2022/1919729
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发表时间：
2022
影响因子：
2
通讯作者：
Liu P
中科院分区：
文献类型：
--
作者：
Yao Q;Peng S;Wu Y;Liu P
胸腔积液（PE）是判断重症急性胰腺炎（SAP）严重程度和预后的重要指标。然而，关于留置胸膜导管（IPC）对SAP的影响和时间的研究很少。因此，我们设计了一项回顾性研究，验证PE与SAP严重程度的关系，观察IPC在SAP中的影响和时间。共入组了309例SAP患者。根据PE、IPC有无及IPC时间将入组患者分为6组。然后比较两组患者的基线参数、疾病严重程度、严重并发症、呼吸机支持时间（VST）、住院时间（LOS）和60天死亡率。PE是SAP患者死亡的危险因素，但不是独立的危险因素。SAP患者合并PE比不合并PE有更高的严重并发症发生率（p < 0.001），以及更长的VST （p < 0.001）和LOS （p < 0.001）。1组（发病1周内IPC）的严重并发症发生率低于2组（发病1周后IPC）。此外，1组患者的LOS （p = 0.042）和VST （p = 0.001）也短于2组。此外，生存分析显示PE组的死亡风险高于非PE组（HR 6.6, 95% CI, 3.67-11.86, p < 0.001）。1组患者死亡风险低于2组（HR 0.26, 95% CI 0.08 ~ 0.84, p = 0.025）。PE是SAP患者死亡的危险因素，但不是独立的危险因素。IPC，特别是发病1周内的IPC，在SAP中具有临床实用价值。
Pleural effusion (PE) is an important predictor for severity and prognosis of severe acute pancreatitis (SAP). However, there are few studies focused on the effects and timing of indwelling pleural catheter (IPC) on SAP. Considering this, we designed a retrospective study to verify the relationship between PE and severity of SAP and observe the effects and timing of IPC in SAP. A total of 309 SAP patients were enrolled. Based on the presence or absence of PE and IPC and IPC time, the enrolled patients were divided into 6 groups. Then, baseline parameters, disease severity, critical complications, ventilator supporting time (VST), length of stay (LOS), and 60-day mortality were compared between each two groups. PE was a risk factor for death of SAP, but not an independent risk factor. SAP patients with PE rather without PE had higher critical complication rates (p < 0.001), along with longer VST (p < 0.001) and LOS (p < 0.001). And the critical complication rates were lower in group 1 (IPC within 1 week of onset) than group 2 (IPC after 1 week of onset). Further, patients in group 1 also had shorter LOS (p = 0.042) and VST (p = 0.001) than those in group 2. In addition, the survival analysis showed the risk of death in the PE group was higher than the non-PE group (HR 6.6, 95% CI, 3.67–11.86, and p < 0.001). And the risk of death in group 1 was lower than group 2 (HR 0.26, 95% CI, 0.08–0.84, and p = 0.025). PE is a risk factor for death of SAP, but not an independent risk factor. IPC, especially IPC within 1 week of onset, has clinical practical value in SAP.
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影响因子：
4
作者：
He, Fang;Zhu, Hong-ming;Zhang, Mei
通讯作者：
Zhang, Mei
影响因子：
24.5
作者：
Johnson, CD;Kingsnorth, AN;Curtis, LD
通讯作者：
Curtis, LD
影响因子：
0.8
作者：
Ng, Boon Hau;Nik Abeed, Nik Nuratiqah;Ban, Andrea Yu-Lin
通讯作者：
Ban, Andrea Yu-Lin
影响因子：
2.9
作者：
De Waele, Jan J.;Delrue, Louke;Colardyn, Francis A.
通讯作者：
Colardyn, Francis A.
DOI：
10.12659/msm.928118
发表时间：
2021-03-08
期刊：
Medical science monitor : international medical journal of experimental and clinical research
影响因子：
--
作者：
Zeng QX;Jiang KL;Wu ZH;Huang DL;Huang YS;Zhuang HW;Zhong HJ
通讯作者：
Zhong HJ