CT of Post-Acute Lung Complications of COVID-19.
CT of Post-Acute Lung Complications of COVID-19.
复制标题
COVID-19的急性肺后并发症的CT。
DOI：
10.1148/radiol.2021211396
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发表时间：
2021-11
期刊：
影响因子：
19.7
通讯作者：
Lynch DA
中科院分区：
文献类型：
--
作者：
Solomon JJ;Heyman B;Ko JP;Condos R;Lynch DA
2019冠状病毒病（COVID-19）的急性病程是可变的，从无症状感染到暴发性呼吸衰竭。从COVID-19中恢复的患者可能有持续的症状和不同严重程度的计算机断层扫描（CT）异常。在急性感染后3个月，一部分患者将出现CT异常，包括磨玻璃样异常（GGO）和胸膜下带伴肺功能异常。在急性感染后6个月，一些患者出现持续性CT变化，包括在早期恢复期观察到的甘精胰岛素消退和提示纤维化的变化持续或发展，如网状影伴或不伴实质扭曲。COVID后肺部疾病的预测因素包括需要重症监护室（ICU）入院、机械通气、较高的炎症标志物、较长的住院时间和急性呼吸窘迫综合征（ARDS）的诊断。目前正在研究COVID后肺部疾病的治疗方法，并正在研究用于预防COVID后肺纤维化的抗纤维化药物。COVID后肺部疾病的病因可能是长时间机械通气的后遗症、COVID诱导的ARDS或病毒的直接损伤。未来的研究需要确定COVID后肺部疾病的长期持续性，其对患者的影响以及预防或治疗方法。
The acute course of coronavirus disease 2019 (COVID-19) is variable and ranges from asymptomatic infection to fulminant respiratory failure. Patients recovering from COVID-19 can have persistent symptoms and computed tomography (CT) abnormalities of variable severity. At 3 months after acute infection, a subset of patients will have CT abnormalities that include ground glass abnormalities (GGO) and subpleural bands with concomitant pulmonary function abnormalities. At 6 months after acute infection, some patients have persistent CT changes to include the resolution of GGOs seen in the early recovery phase and the persistence or development of changes suggestive of fibrosis such as reticulation with or without parenchymal distortion. Predictors of post-COVID lung disease include need for intensive care unit (ICU) admission, mechanical ventilation, higher inflammatory markers, longer hospital stay and a diagnosis of acute respiratory distress syndrome (ARDS). Treatments of post-COVID lung disease are being investigated with anti-fibrotic agents being investigated for the prevention of post-COVID lung fibrosis. The etiology of post-COVID lung disease may be a sequela of prolonged mechanical ventilation, COVID-induced ARDS or direct injury from the virus. Future research is needed to determine the long-term persistence of post-COVID lung disease, its impact on patients and ways to prevent or treat it.
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影响因子：
8.8
作者：
Burnham EL;Hyzy RC;Paine R 3rd;Coley C 2nd;Kelly AM;Quint LE;Lynch D;Janssen WJ;Moss M;Standiford TJ
通讯作者：
Standiford TJ
DOI：
10.4103/ijri.ijri_469_16
发表时间：
2017-07
期刊：
The Indian journal of radiology & imaging
影响因子：
--
作者：
Das KM;Lee EY;Singh R;Enani MA;Al Dossari K;Van Gorkom K;Larsson SG;Langer RD
通讯作者：
Langer RD
影响因子：
2.1
作者：
Cau R;Pacielli A;Fatemeh H;Vaudano P;Arru C;Crivelli P;Stranieri G;Suri JS;Mannelli L;Conti M;Mahammedi A;Kalra M;Saba L
通讯作者：
Saba L
影响因子：
13.8
作者：
Bravata DM;Perkins AJ;Myers LJ;Arling G;Zhang Y;Zillich AJ;Reese L;Dysangco A;Agarwal R;Myers J;Austin C;Sexson A;Leonard SJ;Dev S;Keyhani S
通讯作者：
Keyhani S
影响因子：
3.6
作者：
Cherry JD;Krogstad P
通讯作者：
Krogstad P