Pathway Logic

Pathway Logic
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通路逻辑

DOI:
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发表时间:
2008
期刊:
International School on Formal Methods for the Design of Computer, Communication and Software Systems
影响因子:
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通讯作者:
C. Talcott
C. Talcott
中科院分区:
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文献类型:
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作者:
C. Talcott

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路径逻辑(Pathway Logic,PL)是一种基于重写逻辑的生物过程建模和分析方法。本教程介绍了使用PL来模拟信号转导过程。它开始于符号系统生物学的一般讨论,其次是重写逻辑和信号转导的一些背景。对一个小模型Ras和Raf的激活进行了详细的描述和分析。随后讨论了响应于表皮生长因子刺激的早期信号传导事件的策划模型。
Pathway Logic (PL) is an approach to modeling and analysis of biological processes based on rewriting logic. This tutorial describes the use of PL to model signal transduction processes. It begins with a general discussion of Symbolic Systems Biology, followed by some background on rewriting logic and signal transduction. The representation and analysis of a small model Ras and Raf activation is presented in some detail. This is followed by discussion of a curated model of early signaling events in response to Epidermal Growth Factor stimulation.
DOI: 10.1210/edrv.22.2.0428
发表时间: 2001-04
期刊: Endocrine reviews
影响因子: 20.3
作者:
G. Pearson;Fred L Robinson;T. Gibson;Bing-e Xu;M. Karandikar;K. Berman;M. Cobb
通讯作者: G. Pearson;Fred L Robinson;T. Gibson;Bing-e Xu;M. Karandikar;K. Berman;M. Cobb